CBSE Questions for Class 12 Medical Biology Molecular Basis Of Inheritance Quiz 11 - MCQExams.com

Which is not true about the genetic code?
  • It is exactly the same in all organisms
  • It is composed of a tripletcode of three bases per codon
  • It produces 64 different possibilities of base sequences
  • It contains start and stop codons as instructions
Choose the correct answers from the alternatives given :
The creation of an RNA molecule from a section of DNA is known as
  • replication
  • RNA splicing
  • transcription
  • translation
Choose the correct answers from the alternatives given :
Which of the following is not true of a codon?
  • It extends from one end of a tRNA molecule
  • It never codes for more than one amino acid
  • It may code for the same amino acid as another codon does
  • It consists of three nucleotides
In  a dsDNA number of phosphodiester bonds are $$3250$$, then find the number of base pairs.
  • $$1625$$
  • $$1626$$
  • $$3252$$
  • $$3250$$
Purines have nitrogen atoms at ______ positions.
  • 1',3',7',9'
  • 1',5',7',9'
  • 1',3'
  • 1',9'
In a DNA molecule, the phosphate group is attached to ____carbon of the sugar residue of its own nucleotide and _____ carbon of the sugar residue of the next nucleotide by ____bonds.
  • 5', 3', phosphodiester
  • 5', 3', glycosidic
  • 3', 5', phosphodiester
  • 3', 5', glycosidic
Choose the correct answer from the alternatives given, Human genome consists of approximately
  • $$3 \, \times \, 10^9$$ bp
  • $$6 \, \times \, 10^9$$ bp
  • 20,000 + 25,000 bp
  • $$2.2 \, \times \, 10^4$$ bp
Choose the correct answer from the alternatives given :
An organism uses 20 amino acids while its DNA is made up of 6 types of nitrogenous bases. What would be the minimum size of a codon?
  • 6
  • 4
  • 3
  • 2

Which bonds are indicated by X and Y in the given diagram?

885545_bb5daafdb04d4c7389ddc1d5a463b1c3.PNG
  • X - Glycosidic bond
    Y - Hydrogen bond
  • X - Phosphodiester bond
    Y - Hydrogen bond
  • X - Glycosidic bond
    Y - Phosphodiester bond
  • X - Phosphodiester bond
    Y - Glycosidic bond
B-DNA which is right-handed double helix contains ______ base pairs per turn of the helix and each turn is _______ long.
  • 10, 3.4 $$\mathring {A} $$
  • 10, 34 $$\mathring {A}$$
  • 11, 20 $$\mathring {A}$$
  • 11, 34 $$\mathring {A}$$
Choose the correct answer from the alternatives given :
In a DNA strand the nucleotides are linked together by
  • Glycosidic bonds
  • Phosphodiester bonds
  • Peptide bonds
  • Hydrogen bonds
Fill up the blanks and select the correct option.
(i) EcoRI cuts the DNA between bases ___  and ____ when the sequence _____  is present in the DNA.
(ii) Disruption of the cell membranes can be achieved by treating the bacterial cells, plant cells and fungal cells with enzymes respectively ____, ____ and ___.
(iii) Since DNA has a ____ charge, it moves towards the ____ of the electrophoretic chamber.
  • (i) G, A, GAATTC (ii) endonuclease, cellulase, chitinase (iii) negative, anode
  • (i) G, A, GAATTC (ii) lysozyme, cellulase, chitinase (iii) positive, cathode
  • (i) G, A, GAATTC (ii) lysozyme, cellulase, chitinase (iii) negative/anode
  • (i) G, A, GAAATC (ii) lysozyme, cellulase, chitinase (iii) positive, cathode
Pyrimidines have nitrogen atoms at ____positions.
  • 1',3',7',9'
  • 1',5',7',9'
  • 1',3'
  • 1',9'
Which out of the following statements is incorrect?
  • Genetic code is ambiguous.
  • Genetic code is degenerate.
  • Genetic code is universal.
  • Genetic code is non-overlapping.
Choose the correct answer from the alternatives given :
The semi-conservative nature of DNA replication was established by Meselson and Stahl in their classic experiment with bacteria They grew bacteria in $$N^{15} \, - \, NH_4Cl$$ containing medium, washed and then incubated in fresh medium with $$N^{14}$$ - containing compounds and allowed to grow for three generations. $$C_5Cl$$ density gradient centrifugation of isolated DNA established the nature of semiconservative DNA Replication. The pictorial representation below shows the position of differentially labeled DNA in $$C_5Cl$$ density gradient. Had the DNA replication been conservative, what would have been the pattern?
928712_27a6cef2ba7c47bc9e230f9f29d78914.png
The amino acid attaches to the tRNA at its
  • 5' - end
  • 3' - end
  • Anticodon site
  • DHU loop
Which of the following Is correct regarding genetic code?
  • UUU is the initiation codon which also codes for phenylalanine.
  • There are 64 triplet codons and only 20 amino adds.
  • Three random nitrogen bases specify the placement of one amino acid.
  • UAA is the nonsense codon which also codes for methionine.
The sequencing of the entire genome (the totality of all genes) of an organism was completed inThe organism was
  • Human being
  • Yeast
  • Albino mouse
  • Plasmodium vivax
Find the sequence of binding of the following amino acyl-tRNA complexes during translation of an mRNA transcribed by a DNA segment having the base sequence 3'TACATGGGTCCG5'. Choose the answer showing the correct order of alphabets.
931255_85baeb3fd94940ee8b9cdcc3a74432cd.png
  • P, Q, S, R
  • Q, P, S, R
  • P, Q, R, S
  • Q, P, R, S
Which of the following biologists has been dubbed as the architect of molecular biology?
  • Francis Crick
  • Frederick Sanger
  • Jacques Lucien Monod
  • James Watson
One of the following is true with respect to AUG
  • it codes for methionine only
  • it is also an initiation codon
  • it codes for methionine in both prokaryotes and eukaryotes
  • all of the above
Which of the following option shows correct matching of Column - I and Column - II.
Column - IColumn - II
(i) Degeneration codon(a) AUG
(ii) Initiation codon(b) UAG
(iii) Non - sense codons(c) AGU
(iv) Anti codon (UCA)(d) AGA

  • (i - c) (ii - b) (iii - a) (iv - d)
  • (i - d) (ii - a) (iii - b) (iv - c)
  • (i - b) (ii - d) (iii - a) (iv - c)
  • (i - d) (ii - c) (iii - b) (iv - a)
The technique of DNA finger printing was initially developed by 
  • lan wilmut
  • Hargobind Khorana
  • Jacque Monod
  • Alec Jeffreys
  • Francois Jacob
Basis of DNA fingerprinting is
  • relative proportion of purines and pyrimidines
  • relative difference in DNA occurrence in blood, skin and saliva
  • relative amounts of DNA in ridges and groves of fingerprints
  • satellite DNA occuring as highly short DNA segments.
The toxin produced by the bacteria that is responsible for the development of diarrhea is produced by a section of DNA that has the code CCT TAT CAG. The sequence of amino acids produced by this sequence is ____________.
  • Glycine - isoleucine - aspartic acid
  • Glycine - isoleucine - valine
  • Glycine - tyrosine - valine
  • Glycine - tyrosine - isoleucine
Select the correct one in reference to Wobble hypothesis.
  • Third base of codon lacks vibrating capacity.
  • Third base can establish H-bonds even with the non-complementary anticodon.
  • Specificity of a anticodon is particularly determined by first two codon.
  • Major cause of degeneracy is the first two N-bases of codon.
Teminism is same as _____.
  • Transcription
  • Translation
  • Reverse transcription
  • DNA synthesis
1.38 milimeter DNA is present in E. coli. How many base pair will be present in it?
  • $$4 \times 10^6 bp$$
  • $$4 \times 10^7 bp$$
  • $$4 \times 10^8 bp$$
  • $$4 \times 10^5 bp$$
Name the enzyme which removes the non coding split genes
  • Ribosome
  • Lysozyme
  • Ribozyme
  • Helicase
Transfer of information from molecule of DNA to mRNA is called as 
  • Transcription
  • Translation
  • Replication
  • None of the above
Replication in prokaryotes differ from replication in eukaryotes for which of the following reasons?
  • Prokaryotes have telomeres but eukaryotes do not
  • Prokaryotes produces Okazaki fragments but eukaryotes do not
  • The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes
  • Prokaryotes have a single origin of replication (ori -site) whereas eukaryotes have many ori -sites
Calculate the number of nitrogen bases in E.coli, if the length of E.coli DNA is 1.36 mm.
  • $$4 \times 10^6$$
  • $$8 \times 10^6$$
  • $$2 \times 10^6$$
  • $$16 \times 10^6$$
Light DNA ($$14_N$$) transferred to $$15_N$$ labelled culture medium for replication. The ratio of the total number of $$15_N$$ and $$14_N$$ labeled strands of DNA extracted from the culture after three generations is
  • 1 : 3
  • 7 : 1
  • 1 : 15
  • 15 : 1
If a triplet on template DNA is AAA, what will be the anticodon on tRNA
  • UUU
  • AAA
  • TTT
  • AUG
All living organisms of the present,past and future are 
  • Not linked to any extent
  • Linked to one another in their cell membrane
  • Linked to one another by the sharing of the common genetic materials ,but to varying degrees
  • Linked to another by the sharing of the common genetic material to $$100\%$$ extent
Maximum possible transversion, which may take place in genetic code
  • $$366$$
  • $$183$$
  • $$549$$
  • In each coden $$9$$ only
By using only one of the two strands of DNA, mRNA is produced this process is called as _____
  • Transcription
  • Translation
  • Translocation
  • Replacement
Purine base of DNA molecule has 
  • A and C
  • C and T
  • A and G
  • None of the above
The ratio of $$H_1$$ and $$H_3$$ proteins in chromatin is
  • $$1:2$$
  • $$2:1$$
  • $$1:1$$
  • $$1:4$$
Sequencing of genomic DNA is included under
  • Structural genomics
  • Functional genomics
  • Proteomics
  • Transgenesis
Read the statements given below.

I. Thiamine and Uracil are pyrimidines found in DNA & RNA respectively.
II. Number of base pairs per turn in B - DNA helix is 10.

Choose the correct option.
  • Both statements I & II are correct
  • Only statement II is correct
  • Both statement I & II are incorrect
  • Only statement I is correct.
No. of of phosphoester bonds found in one turn of DNA is ____________.
  • $$18$$
  • $$10$$
  • $$40$$
  • $$38$$
Sometimes the starting codon is GUG in place of AUG, GUG normally stands for ___________.
  • Valine
  • Glycine
  • Methionine
  • Tyrosine
Which enzyme polymerizes RNA with defined sequence in a template independent manner?
  • Peptidyl transferase
  • RNA Polymerase
  • Reverse transcription
  • Polynucleotide phosphorylase
How many among the following organisms hve linear ds DNA as their genetic material?
Homo sapiens, Escherichia coil, Drosophila, $$\phi \times 174$$ bacteriophage
  • $$1$$
  • $$4$$
  • $$3$$
  • $$2$$
Complete the steps for the separation and isolation of $$DNA$$ fragments.
  (i) $$DNA$$ fragment separates in matrix of________.
  (ii) $$DNA$$ fragments are stained with______
  (iii) $$DNA$$ fragments are viewed under_________
  (iv) Fragments are extruded from gel piece. This is called________
  • Agarose gels,ethidium bromide, UV light, elution
  • Polyacrylamide gels, ethidium bromide, UV light, elution
  • Polyacrylamide gels, ethidium bromide, X-ray light, elution
  • Agarose gels,ethidium bromide, X- ray light, extraction
If heat killed S-III and live R-II are mixed then?
  • Something from S-III enters into R-II
  • Something from R-II enters into S-III
  • R-II receives material its nature changes
  • A and C both
The following picture depicts the DNA .What is the structure of DNA ?
1293137_ac42fbe526e846efa9d5cb2e98b67369.JPG
  • Spherical
  • Double Helix
  • Dumbell
  • Renal and longitudinal
In bacteria, DNA has no free ends and is not associated with
  • Polyamines
  • Histone
  • RNA
  • More than one option is correct
Read the given statement and statements and select the correct option.
Statement 1: The alien DNA is cloned in the host organism by integrating it in host DNA.
statement II: The  alien DNA has specific DNA sequence called origin of replication, which help it join to host genome.
  • statement I is correct, statement II is incorrect.
  • statement i is incorrect, statement II is correct.
  • Both statements I and II are correct
  • Both statements I and II are incorrect
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