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CBSE Questions for Class 12 Medical Biology Molecular Basis Of Inheritance Quiz 11 - MCQExams.com

Which is not true about the genetic code?
  • It is exactly the same in all organisms
  • It is composed of a tripletcode of three bases per codon
  • It produces 64 different possibilities of base sequences
  • It contains start and stop codons as instructions
Choose the correct answers from the alternatives given :
The creation of an RNA molecule from a section of DNA is known as
  • replication
  • RNA splicing
  • transcription
  • translation
Choose the correct answers from the alternatives given :
Which of the following is not true of a codon?
  • It extends from one end of a tRNA molecule
  • It never codes for more than one amino acid
  • It may code for the same amino acid as another codon does
  • It consists of three nucleotides
In  a dsDNA number of phosphodiester bonds are 3250, then find the number of base pairs.
  • 1625
  • 1626
  • 3252
  • 3250
Purines have nitrogen atoms at ______ positions.
  • 1',3',7',9'
  • 1',5',7',9'
  • 1',3'
  • 1',9'
In a DNA molecule, the phosphate group is attached to ____carbon of the sugar residue of its own nucleotide and _____ carbon of the sugar residue of the next nucleotide by ____bonds.
  • 5', 3', phosphodiester
  • 5', 3', glycosidic
  • 3', 5', phosphodiester
  • 3', 5', glycosidic
Choose the correct answer from the alternatives given, Human genome consists of approximately
  • 3×109 bp
  • 6×109 bp
  • 20,000 + 25,000 bp
  • 2.2×104 bp
Choose the correct answer from the alternatives given :
An organism uses 20 amino acids while its DNA is made up of 6 types of nitrogenous bases. What would be the minimum size of a codon?
  • 6
  • 4
  • 3
  • 2

Which bonds are indicated by X and Y in the given diagram?

885545_bb5daafdb04d4c7389ddc1d5a463b1c3.PNG
  • X - Glycosidic bond
    Y - Hydrogen bond
  • X - Phosphodiester bond
    Y - Hydrogen bond
  • X - Glycosidic bond
    Y - Phosphodiester bond
  • X - Phosphodiester bond
    Y - Glycosidic bond
B-DNA which is right-handed double helix contains ______ base pairs per turn of the helix and each turn is _______ long.
  • 10, 3.4 ˚A
  • 10, 34 ˚A
  • 11, 20 ˚A
  • 11, 34 ˚A
Choose the correct answer from the alternatives given :
In a DNA strand the nucleotides are linked together by
  • Glycosidic bonds
  • Phosphodiester bonds
  • Peptide bonds
  • Hydrogen bonds
Fill up the blanks and select the correct option.
(i) EcoRI cuts the DNA between bases ___  and ____ when the sequence _____  is present in the DNA.
(ii) Disruption of the cell membranes can be achieved by treating the bacterial cells, plant cells and fungal cells with enzymes respectively ____, ____ and ___.
(iii) Since DNA has a ____ charge, it moves towards the ____ of the electrophoretic chamber.
  • (i) G, A, GAATTC (ii) endonuclease, cellulase, chitinase (iii) negative, anode
  • (i) G, A, GAATTC (ii) lysozyme, cellulase, chitinase (iii) positive, cathode
  • (i) G, A, GAATTC (ii) lysozyme, cellulase, chitinase (iii) negative/anode
  • (i) G, A, GAAATC (ii) lysozyme, cellulase, chitinase (iii) positive, cathode
Pyrimidines have nitrogen atoms at ____positions.
  • 1',3',7',9'
  • 1',5',7',9'
  • 1',3'
  • 1',9'
Which out of the following statements is incorrect?
  • Genetic code is ambiguous.
  • Genetic code is degenerate.
  • Genetic code is universal.
  • Genetic code is non-overlapping.
Choose the correct answer from the alternatives given :
The semi-conservative nature of DNA replication was established by Meselson and Stahl in their classic experiment with bacteria They grew bacteria in N15NH4Cl containing medium, washed and then incubated in fresh medium with N14 - containing compounds and allowed to grow for three generations. C5Cl density gradient centrifugation of isolated DNA established the nature of semiconservative DNA Replication. The pictorial representation below shows the position of differentially labeled DNA in C5Cl density gradient. Had the DNA replication been conservative, what would have been the pattern?
928712_27a6cef2ba7c47bc9e230f9f29d78914.png
The amino acid attaches to the tRNA at its
  • 5' - end
  • 3' - end
  • Anticodon site
  • DHU loop
Which of the following Is correct regarding genetic code?
  • UUU is the initiation codon which also codes for phenylalanine.
  • There are 64 triplet codons and only 20 amino adds.
  • Three random nitrogen bases specify the placement of one amino acid.
  • UAA is the nonsense codon which also codes for methionine.
The sequencing of the entire genome (the totality of all genes) of an organism was completed inThe organism was
  • Human being
  • Yeast
  • Albino mouse
  • Plasmodium vivax
Find the sequence of binding of the following amino acyl-tRNA complexes during translation of an mRNA transcribed by a DNA segment having the base sequence 3'TACATGGGTCCG5'. Choose the answer showing the correct order of alphabets.
931255_85baeb3fd94940ee8b9cdcc3a74432cd.png
  • P, Q, S, R
  • Q, P, S, R
  • P, Q, R, S
  • Q, P, R, S
Which of the following biologists has been dubbed as the architect of molecular biology?
  • Francis Crick
  • Frederick Sanger
  • Jacques Lucien Monod
  • James Watson
One of the following is true with respect to AUG
  • it codes for methionine only
  • it is also an initiation codon
  • it codes for methionine in both prokaryotes and eukaryotes
  • all of the above
Which of the following option shows correct matching of Column - I and Column - II.
Column - IColumn - II
(i) Degeneration codon(a) AUG
(ii) Initiation codon(b) UAG
(iii) Non - sense codons(c) AGU
(iv) Anti codon (UCA)(d) AGA

  • (i - c) (ii - b) (iii - a) (iv - d)
  • (i - d) (ii - a) (iii - b) (iv - c)
  • (i - b) (ii - d) (iii - a) (iv - c)
  • (i - d) (ii - c) (iii - b) (iv - a)
The technique of DNA finger printing was initially developed by 
  • lan wilmut
  • Hargobind Khorana
  • Jacque Monod
  • Alec Jeffreys
  • Francois Jacob
Basis of DNA fingerprinting is
  • relative proportion of purines and pyrimidines
  • relative difference in DNA occurrence in blood, skin and saliva
  • relative amounts of DNA in ridges and groves of fingerprints
  • satellite DNA occuring as highly short DNA segments.
The toxin produced by the bacteria that is responsible for the development of diarrhea is produced by a section of DNA that has the code CCT TAT CAG. The sequence of amino acids produced by this sequence is ____________.
  • Glycine - isoleucine - aspartic acid
  • Glycine - isoleucine - valine
  • Glycine - tyrosine - valine
  • Glycine - tyrosine - isoleucine
Select the correct one in reference to Wobble hypothesis.
  • Third base of codon lacks vibrating capacity.
  • Third base can establish H-bonds even with the non-complementary anticodon.
  • Specificity of a anticodon is particularly determined by first two codon.
  • Major cause of degeneracy is the first two N-bases of codon.
Teminism is same as _____.
  • Transcription
  • Translation
  • Reverse transcription
  • DNA synthesis
1.38 milimeter DNA is present in E. coli. How many base pair will be present in it?
  • 4×106bp
  • 4×107bp
  • 4×108bp
  • 4×105bp
Name the enzyme which removes the non coding split genes
  • Ribosome
  • Lysozyme
  • Ribozyme
  • Helicase
Transfer of information from molecule of DNA to mRNA is called as 
  • Transcription
  • Translation
  • Replication
  • None of the above
Replication in prokaryotes differ from replication in eukaryotes for which of the following reasons?
  • Prokaryotes have telomeres but eukaryotes do not
  • Prokaryotes produces Okazaki fragments but eukaryotes do not
  • The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes
  • Prokaryotes have a single origin of replication (ori -site) whereas eukaryotes have many ori -sites
Calculate the number of nitrogen bases in E.coli, if the length of E.coli DNA is 1.36 mm.
  • 4×106
  • 8×106
  • 2×106
  • 16×106
Light DNA (14N) transferred to 15N labelled culture medium for replication. The ratio of the total number of 15N and 14N labeled strands of DNA extracted from the culture after three generations is
  • 1 : 3
  • 7 : 1
  • 1 : 15
  • 15 : 1
If a triplet on template DNA is AAA, what will be the anticodon on tRNA
  • UUU
  • AAA
  • TTT
  • AUG
All living organisms of the present,past and future are 
  • Not linked to any extent
  • Linked to one another in their cell membrane
  • Linked to one another by the sharing of the common genetic materials ,but to varying degrees
  • Linked to another by the sharing of the common genetic material to 100% extent
Maximum possible transversion, which may take place in genetic code
  • 366
  • 183
  • 549
  • In each coden 9 only
By using only one of the two strands of DNA, mRNA is produced this process is called as _____
  • Transcription
  • Translation
  • Translocation
  • Replacement
Purine base of DNA molecule has 
  • A and C
  • C and T
  • A and G
  • None of the above
The ratio of H1 and H3 proteins in chromatin is
  • 1:2
  • 2:1
  • 1:1
  • 1:4
Sequencing of genomic DNA is included under
  • Structural genomics
  • Functional genomics
  • Proteomics
  • Transgenesis
Read the statements given below.

I. Thiamine and Uracil are pyrimidines found in DNA & RNA respectively.
II. Number of base pairs per turn in B - DNA helix is 10.

Choose the correct option.
  • Both statements I & II are correct
  • Only statement II is correct
  • Both statement I & II are incorrect
  • Only statement I is correct.
No. of of phosphoester bonds found in one turn of DNA is ____________.
  • 18
  • 10
  • 40
  • 38
Sometimes the starting codon is GUG in place of AUG, GUG normally stands for ___________.
  • Valine
  • Glycine
  • Methionine
  • Tyrosine
Which enzyme polymerizes RNA with defined sequence in a template independent manner?
  • Peptidyl transferase
  • RNA Polymerase
  • Reverse transcription
  • Polynucleotide phosphorylase
How many among the following organisms hve linear ds DNA as their genetic material?
Homo sapiens, Escherichia coil, Drosophila, ϕ×174 bacteriophage
  • 1
  • 4
  • 3
  • 2
Complete the steps for the separation and isolation of DNA fragments.
  (i) DNA fragment separates in matrix of________.
  (ii) DNA fragments are stained with______
  (iii) DNA fragments are viewed under_________
  (iv) Fragments are extruded from gel piece. This is called________
  • Agarose gels,ethidium bromide, UV light, elution
  • Polyacrylamide gels, ethidium bromide, UV light, elution
  • Polyacrylamide gels, ethidium bromide, X-ray light, elution
  • Agarose gels,ethidium bromide, X- ray light, extraction
If heat killed S-III and live R-II are mixed then?
  • Something from S-III enters into R-II
  • Something from R-II enters into S-III
  • R-II receives material its nature changes
  • A and C both
The following picture depicts the DNA .What is the structure of DNA ?
1293137_ac42fbe526e846efa9d5cb2e98b67369.JPG
  • Spherical
  • Double Helix
  • Dumbell
  • Renal and longitudinal
In bacteria, DNA has no free ends and is not associated with
  • Polyamines
  • Histone
  • RNA
  • More than one option is correct
Read the given statement and statements and select the correct option.
Statement 1: The alien DNA is cloned in the host organism by integrating it in host DNA.
statement II: The  alien DNA has specific DNA sequence called origin of replication, which help it join to host genome.
  • statement I is correct, statement II is incorrect.
  • statement i is incorrect, statement II is correct.
  • Both statements I and II are correct
  • Both statements I and II are incorrect
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Practice Class 12 Medical Biology Quiz Questions and Answers