CBSE Questions for Class 12 Medical Biology Molecular Basis Of Inheritance Quiz 4 - MCQExams.com

Which of the following is a stop codon?
  • AUG, GUG, UUU
  • UGA, UAG, UAA
  • UUU, UAC, CUC
  • CUC, UAC, UAA
The double helix model of Watson and Crick is known as
  • C-DNA
  • B-DNA
  • Z-DNA
  • D-DNA
DNA fingerprinting was invented by
  • Kary Mullis
  • AIec Jeffery
  • Dr. Paul Berg
  • Francis Collins
The enzyme involved in transcription is
  • RNA polymerase
  • DNA polymerase I
  • DNA polymerase II
  • DNA polymerase III
A codon is made up of
  • Single nucleotide
  • Two nucleotides
  • Three nucleotides
  • Four nucleotides
Multiplication of DNA is called as
  • Translation
  • Replication
  • Transduction
  • Transcription
Which of the following enzyme is used in DNA multiplication?
  • RNA polymerase
  • DNA endonuclease
  • Exonuclease
  • DNA polymerase
Which of the following enzyme is used to join DNA fragments?
  • Terminase
  • Endonuclease
  • Ligase
  • DNA polymerase
Method by which information reaches from DNA to RNA is
  • Transcription
  • Translation
  • Transformation
  • Transduction
DNA replication requires which of the following enzymes?
  • DNA polymerase only
  • DNA polymerase and ligase
  • Ligase only
  • RNA polymerase
Which of the following is initiator codon?
  • UUU
  • AUC
  • UAC
  • AUG
Initiation codon is
  • AUG
  • UAG
  • UGA
  • UAU
Formation of mRNA from DNA is called as
  • Translation
  • Transcription
  • Transformation
  • Transduction
DNA replication includes which of the following enzymes?
  • DNA ligase
  • DNA polymerase and ligase
  • RNA polymerase and ligase
  • All of the above
Okazaki fragments are synthesized on
  • Leading strands of DNA only
  • Lagging strands of DNA only
  • Both leading and lagging strands of DNA
  • Complementary DNA
Which one of the following pairs of terms/names mean one and the same thing?
  • Gene pool - genome
  • Codon - gene
  • Cistron - triplet
  • DNA fingerprinting - DNA profiling
Formation of RNA on DNA template is called as
  • Transduction
  • Transformation
  • Transcription
  • Translation
Which of the following codes for stop signal?
  • UAA
  • UAG
  • UGA
  • All of the above
DNA synthesis takes place by
  • Replication
  • One polypeptide
  • Many polypeptides
  • All of the above
The direction of DNA replication is
  • From 5' end towards 3' end.
  • From 3' end towards 5' end.
  • Amino terminus to carboxyl terminus.
  • Carboxyl terminus to amino terminus.
Portion of gene which is transcribed but not translated is
  • Exon
  • Intron
  • Cistron
  • Codon
Wobble hypothesis for genetic code was given by 
  • Bernfield and Nirenberg
  • Crick
  • Creighton
  • Hedges
If more than one code designates the single amino acid it is 
  • Degenaracy of codon
  • Overlapping of codon
  • Nonsense codons
  • None of the above
The total number of nitrogenous bases in human genom is estimated to be about
  • 3.5 million
  • 35 thousand
  • 35 million
  • 3.3 billion
In DNA replication, the primer is
  • A small deoxyribonucleotide polymer.
  • A small ribonucleotide polymer.
  • Helix destabilizing protein.
  • Enzyme taking part in joining nucleotides of new strand.
Codons that do not code for amino acids are
  • Phosphates
  • ATP
  • Start and stop signals
  • Nonsense
Degeneracy of the genetic code denotes the existence of 
  • Multiple codons for a single amino acid
  • Wobble hypothesis
  • Base triplets that do not code for amino acids
  • All of the above
The main aim of the human genome project is 
  • To develop better techniques for comparing two different human DNA samples
  • To remove disease causing genes from human DNA
  • To introduce new genes into humans
  • To identify the sequence of all the genes present in human DNA
Which of the following is a nucleoside?
  • Adenosine
  • Adenine
  • Deoxyribose
  • Adenylic acid
Which step does not involve in DNA finger printing?
  • Southern blotting
  • Gel electrophoresis
  • Restriction enzyme digestion
  • Northern blotting
Identify the group which contains only pyrimidines.
  • Adenine, cytosine
  • Uracil, cytosine
  • Guanine, uracil and cytosine
  • Adenine, guanine
Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in protein synthesis or as 'start' or 'stop' codon?
  • UCG - Start
  • UUU - Stop
  • UGU - Leucine
  • UAC - tyrosine
The triplet UUU codes for 
  • Leucine
  • Methionine
  • Phenyl alanine
  • Glycine
Degeneracy in the genetic code was found by 
  • Bernfield and Nirenberg
  • Watson and Crick
  • McClintock and Creighton
  • Hedges and Jacob
  • Lagervist
RNA polymerase was isolated from E.coli by 
  • Ochoa
  • Jenard Hurwitz
  • Kornberg
  • All of the above
When a single anticodon can recognize more than one codon of mRNA it is called as
  • Template hypothesis
  • Degeneracy
  • Gene flow hypothesis
  • Collinearity hypothesis
"It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanisms for the genetic material," this is written by 
  • Meselson and Stahl
  • Archibold Garrod
  • Severo Ochoa
  • Watson and Crick
  • Beadle and Tatum
The enzyme DNA polymerase was discovered by _________.
  • Kornberg
  • Okazaki
  • Watson and Crick
  • Stahl and Meselson
  • Jacob and Monod
Which of the following statement is incorrect?
  • Southeren blotting is useful in determining certain genetic defects.
  • Southern blotting is used to generate DNA fingerprints.
  • DNA fingerprints of any two individuals may be similar.
  • DNA fingerprint is a person specific Northern blot.
In genetic coding, triplet codons make possible 64 types of codons. If the genetic code was a doublet instead of a triplet codon, the number of types of codons possible would be
  • 64 types of codons
  • 4 types of codons
  • 24 types of codons
  • 16 types of codons
DNA finger printing technique was discovered by 
  • Wilmut
  • A. Jeffreys
  • Eithoven
  • Kary Mullis
In a double-stranded DNA, the sequence of base pairs in one strand is AGCTAAGC. What is the complementary sequence on the other strand?
  • TCGATTCG
  • UCGAUUCG
  • AGCTAAGC
  • CAUTAUCG
A naturally occurring coding strand composed of alternating C and U residues would result in the formation of polypeptide containing
  • Alternating leu and ser residues
  • Either leu or ser residues
  • Only leu residues
  • Only ser residues
  • Only phe residues
Which of the following help in repairing of DNA?
  • Ligase
  • DNA polymerase I
  • RNA primer
  • DNA polymerase III
Which one of the following pairs are correctly matched with regard to the codon and the amino acid coded by them?
  • UUA - Valine
  • AAA - Lysine
  • AUG - Cysteine
  • CCC - Alanine
DNA strands
  • Have quaternary structure like protein
  • Are bonded by disulphide bonds
  • Have same polarity
  • Are antiparallel
During splicing, the exons are joined and the enzyme which catalyzes this reaction is 
  • RNA ligase
  • RNA catalase
  • RNA polymerase
  • RNA primase
The sigma factor is associated with
  • RNA polymerase
  • RNA ligase
  • DNA polymerase
  • DNA ligase
Which one of the following codons provide the same information as UGC?
  • UGU
  • UGA
  • UAG
  • UGG
Degeneration of a genetic code is attributed to the 
  • First member of a codon
  • Second member of a codon
  • Entire codon
  • Third member of a codon
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