MCQExams
0:0:1
CBSE
JEE
NTSE
NEET
Practice
Homework
×
CBSE Questions for Class 12 Medical Biology Molecular Basis Of Inheritance Quiz 9 - MCQExams.com
CBSE
Class 12 Medical Biology
Molecular Basis Of Inheritance
Quiz 9
Who discovered genetic code
Report Question
0%
Nirenberg
0%
Khorana
0%
Ochoa
0%
Crick
Degeneration of genetic code is due to
Report Question
0%
First member of codons
0%
Second member of codons
0%
Third member of codons
0%
Entire codons
Genetic code is degenerate because
Report Question
0%
Codons have same energy level
0%
Each codon has a different meaning
0%
Each codon has many meanings
0%
Many codons have same meaning
Watson and Crick shared the Nobel Prize for DNA structure with
Report Question
0%
Franklin
0%
Pauling
0%
Wilkins
0%
Tatum
DNA molecule has small units called
Report Question
0%
Purines
0%
Adenine and thymine
0%
Cistron, Muton and Recon
0%
Adenine
From their experiments on Neurospora crassa, Beadle and Tatum proposed
Report Question
0%
One gene one polypeptide hypothesis
0%
One gene one enzyme hypothesis
0%
One gene one function hypothesis
0%
Many genes one enzyme hypothesis
Plant cell can be transformed through
Report Question
0%
Electrolysis
0%
Electroporation
0%
Electrophoresis
0%
Electroduction
Common to both prokaryotes and eukaryotes is
Report Question
0%
Genetic code
0%
E.R.
0%
Histones
0%
Mitotic spindle
All the terminator codons begin with
Report Question
0%
Guanine
0%
Uracil
0%
Cytosine
0%
Adenine
DNA is denatured by
Report Question
0%
Heat
0%
Acid
0%
DNA polymerase
0%
Both A and B
In bacterial DNA replication, synthesis starting from the site of origin of replication
Report Question
0%
Involves RNA primers
0%
Requires telomerase
0%
Proceeds unidirectionally
0%
Moves bidirectionally
DNA model was proposed by
Report Question
0%
Watson and Crick
0%
Franklin and Wilkins
0%
Lederberg and Tatum
0%
Jacob and Monod
DNA fingerprinting is related to _________.
Report Question
0%
Molecular analysis of profiles of DNA samples
0%
Analysis of DNA samples using imprinting devices
0%
Techniques used for molecular analysis of different specimens of DNA
0%
Techniques used in identification of finger prints of different persons
Explanation
DNA fingerprinting refers to the molecular analysis of the profile of DNA samples, short nucleotide repeats are important for DNA fingerprinting which vary in number from person to person but are inherited. These are variable number tandem repeats (VNTRs) and can be recognized only through molecular analysis of DNA samples. Allec Jefferys in 1985 discovered this technique for the first time in England.
Hence, the correct answer is option A.
DNA replication occurs in 5' 3' direction because
Report Question
0%
DNA polymerase III can polymerise nucleotides in 5 3 direction
0%
DNA polymerase I carries out editing
0%
DNA polymerase I carries out polymerisation
0%
DNA polymerase II can link up only in 5 3 direction
Who discovered DNA polymerase
Report Question
0%
Okazaki
0%
Kornberg
0%
Meselson and Stahl
0%
Watson and Crick
Which is correctly matched ?
Report Question
0%
Frederick Griffith - Discovered transformation
0%
Linus Pauling - Isolated DNA for first time
0%
Francis Crick - Proposed one gene - one polypeptide hypothesis
0%
George Beadle - Proposed concept of inborn errors
0%
Jacob and Monod Proposed Wobble hypothesis
Denaturation of DNA after heating can be studied by comparing
Report Question
0%
Number of nucleotides
0%
A : T ratio
0%
C: G ratio
0%
Sugar phosphate ratio
Find out the correct options
Frederick Griffith - Transformation
Gamow - Triplet code
Meselson - Isolated DNA
Report Question
0%
1, 2, 3 correct
0%
1, 2 correct
0%
2, 3 correct
0%
1, 3 correct
What is not true for genetic code ?
Report Question
0%
It is degenerate
0%
It is nearly universal
0%
A code in mRNA is read in a noncontiguous fashion
0%
It is unambiguous
Year 2003 was celebrated as 50th anniversary of discovery of
Report Question
0%
Transposons by Mc Clintock
0%
Protoplasm by Dujardin
0%
Nucleus by Robert Brown
0%
Structure of DNA by Watson and Crick
Which amino acid is specified by genetic codes ACU, ACC, ACA, ACG showing degeneracy?
Report Question
0%
Leucine
0%
Methionine
0%
Glycine
0%
Threonine
Whose experiments cracked DNA and discovered triplet nature of genetic code?
Report Question
0%
Beadle and Tatum
0%
Hershey and Chase
0%
Morgan and Sturtevant
0%
Nirenberg and Matthaei
Explanation
Marshall Nirenberg and Heinrich J. Matthaei were the first to reveal the nature of a codon in 1961. So the correct option is ' Nirenberg and Matthaei'.
What does the following signify
Report Question
0%
Amino acid + ATP Aminoacyl AMP + PPi
0%
Chain termination
0%
Activation of amino acids
0%
Elongation of chain
0%
None of the above
Which ones are termination codons?
Report Question
0%
UAA, UAG and UGA
0%
GUA, UAA, UAG
0%
UUC, UUG, UAA
0%
UUA, UAG, UAA
0%
UAA, UCA, UUA
DNA element with ability to change its position is
Report Question
0%
Cistron
0%
Transposon
0%
Intron
0%
Recon
DNA replication requires
Report Question
0%
DNA polymerase
0%
DNA ligase
0%
RNA polymerase
0%
All the above
Removal of introns and joining the exons in a defined order in a transcription unit is
Report Question
0%
Splicing
0%
Capping
0%
Tailing
0%
Transformation
A + G = C + T is applicable to
Report Question
0%
rRNA
0%
tRNA
0%
mRNA
0%
DNA
Which is not an application of DNA fingerprinting?
Report Question
0%
Solving immigration cases
0%
Solving parternity cases
0%
Curing SCID
0%
Identifying gene mutation
Explanation
DNA fingerprinting is used to identify any individual, in forensic sciences and collecting knowledge about gene mutation. This
technology cannot be used for curing any disorder such as s
evere combined immunodeficiency.
Hence the correct option is C.
Pairing of DNA fragments is ______.
Report Question
0%
Staggering
0%
Annealing
0%
Augmenting
0%
Fragmenting
Explanation
Annealing refers to the process of cooling as well as heating two single-stranded oligonucleotides with sequences that are complementary. This process can be used for RNA as well. Also, when there is a decrease in temperature after denaturation the most efficient annealing takes place.
Hence, the correct option is (B).
Which is not salient feature of genetic code
Report Question
0%
Ambiguous
0%
Universal
0%
Specific
0%
Degenerate
Explanation
Genetic code is non-ambiguous. Non- ambiguous code means that there is no ambiguity about a particular code. One codon specifies only one amino acid and not any other. There are 64 codons. Out of 64, 3 are stop codons or nonsense codons, i.e., these do not code for any amino acid and rest 61 code for one of the 20 amino acids. Neither of them code for more than one amino acids except GUG which normally code for valine but in certain conditions it also codes for N-formyl methionine as initiation codon.
So, the correct option is A.
Which is correct
Report Question
0%
Introns are present in mRNA and exons in tRNA
0%
Codons are present in mRNA and anticodons in tRNA
0%
Every intron is a set of three terminator codons
0%
Exons are present in eukaryotes and introns in prokaryotes
Select the incorrect statement.
a. Six codons do not code for any amino acid.
b. Codon reading of mRNA is contiguous.
c. Three codons function as stop codons.
d. Initiator codon AUG codes for methionine.
Report Question
0%
a alone is incorrect
0%
a, b and d are incorrect
0%
a, b and c are incorrect
0%
b, c and d are incorrect
0%
b alone is incorrect
Explanation
A. a alone is incorrect
Solution : Codon reading of mRNA is contiguous and continuous. Three codons code for stopping the protein synthesis which are UAA, UAG and UGA. Initiator codon (AUG) codes for methionine.
So the correct answer is "
a alone is incorrect".
Which is not part of transcription unit
Report Question
0%
Promoter
0%
Terminator
0%
Structural gene
0%
Inducer
The coding segment of DNA contains CAC. Which amino acid is picked up during translation?
Report Question
0%
Leucine
0%
Glutamic acid
0%
Valine
0%
Methionine
Which of the following are required in DNA fingerprinting?
Report Question
0%
Restriction endonuclease
0%
<i>Taq</i> polymerase
0%
Oligonucleotide primers
0%
All the above
Explanation
DNA fingerprinting involves the following steps-
1) Extraction of DNA
2) Digestion of DNA with restriction with endonucleases
3) Gel electrophoresis
4) Fragments of specific sizes having VNTR, multiplied by PCR technique (
Taq
polymerase and o
ligonucleotide primers are used).
5) Transfer of DNA nitrocellulose
6) Use of radiolabeled DNA probe
7) Recognition of repetitive sequences.
Hence, the correct option is (D).
Number of histone molecules in each nucleosome core is
Report Question
0%
14
0%
12
0%
10
0%
8
In Griffiths experiment, the conversion of R- type to S-type of Diplococcus pneumoniae when mixed with heat-killed S-type is called
Report Question
0%
Mutation
0%
Transduction
0%
Transfection
0%
Transformation
Which defines the position and presence of template and coding strands in transcription unit
Report Question
0%
Promoter
0%
Operator
0%
Repressor
0%
Inducer
0%
Structural gene
Explanation
It is a DNA sequence that provides binding site for RNA polymerase and it is the
presence
of promoter in a
transcription unit
that also
defines
the
template and coding strands
.
Option A is correct answer.
Choose the wrong statement regarding the observation drawn from Human Genome Project
Report Question
0%
Repetitive sequences are stretches of RNA
0%
Less than 2% of the genome codes for protein
0%
Chromosome Y has the fewest number of genes
0%
SNPs help in tracing human history
0%
Repetive sequences make up a very large portion of the human genome
Choose the correct statement
Report Question
0%
Haploid content of human DNA is 4.6 x $$10^6$$ bp
0%
A nitrogenous base is linked to pentose sugar through phosphodiester linkage
0%
X-ray diffraction data of Maurice Wilkins and Rosalind Franklin was the basis of Watson and Cricks DNA model
0%
DNA as an acidic substance was first identified by Watson and Crick
0%
Ratios between adenine, thymine, guanine and cytisine are not constant
Report Question
0%
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
0%
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
0%
Assertion is correct but Reason is incorrect
0%
Both Assertion and Reason are incorrect
Explanation
DNA fingerprinting was developed by Alec Jeffrey in 1986. This technique reveals polymorphism in DNA. The DNA fingerprint will be the same for all the cells of an individual. The genome of every human cell contains scattered, short highly repeated segments of DNA sequences. These are called minisatellites or the variable number of tandem repeats (VNTR).
DNA fingerprints are used in archaeology, paleontology, and various medical diagnostics including genetic disorders. The technique is extensively used for the diagnosis of many inherited diseases like huntington's, alzheimer's etc. in prenatal and newborn babies but not helpful in the treatment of these inherited disorders.
So, the correct answer is option C.
Hargobind Khorana contributed to genetic engineering by synthesising
Report Question
0%
Viroid
0%
pBR322
0%
pBR42
0%
Artificial gene
Explanation
Hargobind Khorana was the pioneer in DNA technology who discovered codons or three base sequences in a DNA and was the first to synthesize an artificial gene.
So the correct answer is "Artificial gene".
Which codon does not have tRNA?
Report Question
0%
Start codon
0%
Stop codon
0%
AUG
0%
GGG
0%
UUU
Explanation
A. Start codon is AUG. Since AUG also codes for methionine, it has a tRNA molecule carrying methionine in eukaryotes and formylated methionine in prokaryotes.
B. There are three stop codons UAA, UAG, UGA. These do not code for any amino acid. Hence, they do not have tRNA molecules.
C. AUG codes for methionine. Hence, it has tRNA molecule carrying methionine.
D. GGG codes for glycine and has a tRNA molecule carrying glycine.
E. UUU codes for phenylalanine and has a tRNA molecule carrying phenylalanine.
So, the correct answer is 'Stop codon'.
Arrange the following amino acids on the basis of number of triplet codes
(1) Leucine (2) Tryptophan (3) Valine (4) Phenylalanine
Report Question
0%
3-1-2-4
0%
1-2-3-4
0%
2-4-3-1
0%
2-3-4-1
What is correct about genetic code
Report Question
0%
It has 61 codons for amino acids and 3 stop codons
0%
It is universal and has 3 bases per codon
0%
Some amino acids are coded by multiple codons
0%
All the above
Which aminoacid is determined by 4 genetic codes
Report Question
0%
Leucine (Leu)
0%
Serine (Ser)
0%
Proline (Pro)
0%
Tyrosine (Tyr)
Who shared the Nobel Prize for the discovery of DNA structure
Report Question
0%
Watson, Crick and Franklin
0%
Watson, Crick and Wilkins
0%
Watson, Crick and Pauling
0%
Watson, and Crick only
Which statement is more correct about genetic code?
Report Question
0%
It is absolutely universal
0%
It is nearly universal
0%
It is not universal
0%
It is obselete and of no use
Explanation
A codon specifies the same amino acid in every organism. For instance, UGU codon codes for cysteine in every organism. Thus, the genetic code is absolutely universal.
So, the correct answer is option A.
Which of the following is true with reference to transformation in bacteria
i) Transfer of genetic material is mediated by F factor
ii) Uptake of DNA fragments from the surrounding environment and expression of that genetic information in recipient cell
iii) Transformation experiments were the basis to propose chromosomal theory of inheritance
iv) Transformation was discovered by Griffith in Streptococcus pneumonia
Report Question
0%
i, iv
0%
ii, iii, iv
0%
iii, iv
0%
ii, iv
0:0:1
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
0
Answered
0
Not Answered
0
Not Visited
Correct : 0
Incorrect : 0
Report Question
×
What's an issue?
Question is wrong
Answer is wrong
Other Reason
Want to elaborate a bit more? (optional)
Practice Class 12 Medical Biology Quiz Questions and Answers
<
>
Support mcqexams.com by disabling your adblocker.
×
Please disable the adBlock and continue.
Thank you.
Reload page
