CBSE Questions for Class 12 Medical Biology Principles Of Inheritance And Variation Quiz 3 - MCQExams.com

Who postulated the 'Chromosome Theory of Inheritance'?
  • De Vries
  • Mendel
  • Sutton and Boveri
  • Morgan
A person affected by disease having chromosome complement XXX is having/called
  • Klinefillter's syndrome
  • Down's syndrome
  • Super female
  • Turner's syndrome
This pedigree is of a rare trait, in which children have extra fingers and toes. Which one of the following patterns of inheritance is consistent with this pedigree?
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  • Autosomal recessive
  • Autosomal dominant
  • Y linkage
  • Sex linked recessive
Which one of the following symbols and its representation, used in human pedigree analysis is correct?
Which of the following can be identified by using Pedigree chart?
  • Genetic diseases
  • Genetic diversity
  • Genetic mutation
  • Genetic drift
Sickle cell anaemia is a/an
  • Autosomal dominant inheritance
  • X-linked recessive inheritance
  • Autosomal recessive inheritance
  • X-linked dominant inheritance
The process by which new alleles of a gene are produced can be termed as 
  • Mutation
  • Gene manipulation
  • Genetic engineering
  • None of the above
The monosomic condition in human beings depicted as XO is referred to as 
  • Criminal syndrome
  • Down's syndrome
  • Klinefelter's syndrome
  • Turner's syndrome
What is a mutation?
  • Sudden change in morphology
  • Change in characters
  • Change in heritable characters
  • None of the above
The most striking example of point mutation is found in a disease is called as
  • Night blindness
  • Thalassemia
  • Down's syndrome
  • Sickle-cell anaemia
A man having Klinefelter's syndrome is 
  • Intersex with secondary sexual characters on the side of female
  • Male with secondary sexual characters of female
  • Female with secondary sexual characters of male
  • Normal fertile male
Which of the following is an example of a disease of molecular mutation?
  • Erythroblastosis fetalis
  • Haemophilia
  • Anaemia
  • Sickle-cell anaemia
Which of the following is not a Mendelian disorder?
  • Cystic fibrosis
  • Sickle cell anaemia
  • Colour blindness
  • Haemophilia
  • Turner's syndrome
The number of chromosome in Turner's syndrome is
  • 45
  • 43
  • 44
  • 42
An abnormal human male phenotype involving an extra X chromosome (XXY) is a case of 
  • Down's syndrome
  • Intersex
  • Edward syndrome
  • Klinefelter's syndrome
Match column I with column II and find the correct answer.
  Column I   Column II
 (A) Monoploidy (1) 2n - 1
 (B) Monosomy  (2) 2n + 1
 (C) Nullisomy (3) 2n + 2
 (D) Trisomy (4) 2n - 2
 (E) Tetrasomy (5) n
   (6) 3n
  • A- 5, B- 1, C- 4, D- 2, E- 3
  • A- 5, B- 2, C- 4, D- 1, E- 3
  • A- 6, B- 5, C- 3, D- 4, E- 2
  • A- 2, B- 1, C- 3, D- 6 , E- 5
  • A- 1, B- 5, C- 3, D- 2, E- 4
Mutation rates are affected by 
  • Temperature
  • X-rays
  • $$\gamma$$- and $$\beta$$-radiation
  • All of the above

  List I  List II
 (A) XX-XO, method of sex determination (I) Female heterogametic
 (B) 1.5 X/A ratio (II) Turner's syndrome
 (C) Karyotype 45 (III) Hemiptera
 (D) ZW-ZZ method of sex determination (IV) Metafemale
Match the following.
  • A- I, B- IV, C- III, D- II
  • A- III, B- IV, C- II, D- I
  • A- IV, B- I, C- II, D- III
  • A- I, B- IV, C- II, D- III
If a diploid cell is treated with colchicine, then it becomes 
  • Tetraploid
  • Diploid
  • Triploid
  • Monoploid
Polyploidy can be induced by the application of
  • Auxin
  • Kinetin
  • Colchicine
  • Ethylene
A person may have one gene for normal haemoglobin and one gene for sickle cell haemoglobin. This heterozygous condition is called as
  • Genome
  • Anaemia
  • Gene trait
  • Sickle cell trait
If haploid chromosome number in a cell is 12. The monosomic number will be 
  • 24
  • 21
  • 25
  • 23
The number of chromosomes in Klinefelter's syndrome is
  • 47 (44 + XXY)
  • 47 (44 + XXX)
  • 47 (46 + 1 chromosome 21)
  • None of the above
The condition in which there are more than two complete set of chromosome are present, is called
  • Polytene
  • Monoploidy
  • Polyploidy
  • Aneuploidy
The chromosomal condition in Turner's syndrome is 
  • 21 Trisomy with XY
  • 44 Autosomes + XXY
  • 44 Autosomes + XYY
  • 44 Autosomes + XO
  • 18 Trisomy with XY
In man, which of the following genotypes and phenotypes may be the correct result of aneuploidy in sex chromosomes?
  • 22 pairs + XXY males
  • 22 pairs + XX females
  • 22 pairs + XXXY females
  • 22 pairs + Y females
Which of the following option is correct about human egg?
  • It has one Y chromosome.
  • It has two X chromosomes.
  • It has one X chromosome.
  • It has XY chromosomes.
The genotype of a boy having sexual characters of a girl is:
  • XXX
  • XXY
  • XO
  • XYY
Addition of one or more haploid set of its own genome in an organism results in 
  • Autopolyploidy
  • Allopolyploidy
  • Aneuploidy
  • Diploid
The mutation (mechanism of origin of variations) was suggested by 
  • Mendel
  • Darwin
  • Lamarck
  • De Vries
Turner's syndrome in human is caused by 
  • Autosomal aneuploidy
  • Sex chromosome aneuploidy
  • Polyploidy
  • Point mutation
Sex chromosomes for the first time was discovered in which plant?
  • Sphaerocarpus
  • Pisum sativum
  • Neurospora
  • Lathyrus odoratus
In Klinefelter's syndrome, the sex chromosome compliment is
  • 22A + XXY
  • 22A + XO
  • 22A + XY
  • 22A + XX
Turner's syndrome is an example of 
  • Monosomy
  • Bisomy
  • Trisomy
  • Polyploidy
  • Translocation
XO type of sex determination is seen in 
  • Man
  • Grasshopper
  • Drosophila
  • Birds
  • Horses
If somatic cells of a human male contain a single barr body, the genetic composition of the person would be 
  • XYY
  • XXY
  • XO
  • XXXY
A family has five girls and no son. Probability of son as the 6$$^{th}$$ child will be:
  • 50%
  • 75%
  • 100%
  • 25%
Loss of a X chromosome in a particular cell during its development, results into
  • Diploid individual
  • Triploid individual
  • Gynandromorphs
  • Both (a) and (b)
In human female, barr bodies are formed by
  • Inactivation of mother's X chromosome
  • Inactivation of father's X chromosome
  • Inactivation of both mother's and father's X chromosomes
  • Inactivation of either mother's or father's X chromosome
Lyon hypothesis deals with:
  • Centromere position
  • Genetic compatibility
  • Genetic incompatibility
  • Number of Barr bodies
In human beings, sex is determined 
  • Before fertilization of ovum
  • During 6th week of foetal life when androgens are produced
  • At the time of fertilization of ovum
  • During 7th and 8th weeks of foetal life when gonads differentiate into testis and ovary
Chromosome theory of sex determination was propounded by 
  • Bridges
  • Balbiani
  • Goldschmidt
  • None of the above
Study the statements given below.
X: In humans, the gamete contributed by the male determines whether the child produced will be male or female.
Y: Sex in humans is a polygenic trait depending upon a cumulative effect of some genes on X chromosome and some on Y chromosome.
  • If both X and Y are true and the Y is the correct explanation of the X.
  • If both X and Y are true but Y is not the correct explanation of the X.
  • If X is true but Y is false.
  • If both X and Y are false.
In peas, a pure tall plant (TT) is crossed with a short plant (tt). The homozygous ratio of pure tall plants to short plants in F$$_{2}$$ is
  • 1 : 3
  • 3 : 1
  • 1 : 1
  • 2 : 1
Sex is determined by different factors in various species.
  • True
  • False
Assertion:  Holandric genes are found on Y chromosome.

Reason:  Inheritance of holandric genes are always from father to son.
  • If both the assertion and the reason are true and the reason is a correct explanation of the assertion
  • If both the assertion and reason are true but the reason is not a correct explanation of the assertion
  • If the assertion is true but the reason is false
  • If both the assertion and reason are false
  • If the assertion is false but reason is true
The Hardy-Weinburg principle cannot operate if
  • the population is very large
  • frequent mutations occur in the population
  • the population has no chance of interactions with other populations
  • free interbreeding occurs among all members of the population
The genotype of offspring formed from Tt x tt will be ________.
  • TT and tt
  • Tt and tt
  • Only tt
  • Only TT
The phenotypic ratio between tall and dwarf plants in F$$_2$$ generation is 
  • 3:1
  • 4:1
  • 9:1
  • 5:1
Sudden inheritable change is called as
  • Recombination
  • Mutation
  • Natural selection
  • Segregation
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