CBSE Questions for Class 12 Medical Biology Principles Of Inheritance And Variation Quiz 5 - MCQExams.com

If somatic cells of a human male contain single Barr body, the genetic composition of the person would be
  • XYY
  • XXY
  • XO
  • XXXY
In grasshoppers and moths, there are two pairs of autosomes and 
  • X only
  • X and Y
  • Y only
  • None of the above
Klinefelter's syndrome has chromosome arrangement
  • XX
  • XXY
  • XY
  • XO
In a free martin condition,
  • Female is sterile and male is normal
  • Male is sterile and female is normal
  • Both male and female are sterile
  • Both male and female are normal
Which of the following condition is called as monosomic?
  • 2n+1
  • 2n+2
  • n+1
  • 2n-1
In which of these the sex chromosome have discovered for the first time?
  • Melandrium
  • Nephrolepsis
  • Pinus
  • Sphaerocarpus
Barr body is associated with
  • Sex chromosome of female
  • Sex chromosome of male
  • Autosome of female
  • Autosome of male
Which chromosome set is found in male grasshopper?
  • 2A + XY
  • 2A + XO
  • 2A + YY
  • 2A + XX
Which one of the following is a wrong statement regarding mutations?
  • Deletion and insertion of base pairs cause frameshift mutations.
  • Cancer cells commonly show chromosomal aberrations.
  • UV and $$\gamma$$-rays are mutagens.
  • Change in a single base pair of DNA does not cause mutation.
In sickle cell anaemia, which of the sequences get changed?
  • $${\alpha}$$-chain
  • $${\beta}$$-chain
  • Both A and B
  • None of the above
Which one of the following correctly describes the manner of determining the sex in the given examples?
  • Homozygous sex chromosomes (XX) produce male in Drosophila.
  • Homozygous sex chromosomes (ZZ) determine female sex in birds.
  • XO type of sex chromosomes determine male sex in grasshopper.
  • XO condition in humans as found in Turner's syndrome, determines female sex.
A family has five girls and no son, the probability of the occurance of son in 6$$^{th}$$ child is
  • 1/2
  • 1/5
  • 1
  • 1/4
Match the syndromes and chromosomal abnormalities given in columns.
  List I - Syndrome List II - Chromosomal abnormalities
 A Klinefelter syndrome p Trisomy 13
 B Turner's syndrome q Trisomy 18
 C Super female r 44+XXY
 D Patau's syndrome s 44+XXX
   t 44+XO
  • A- r, B- t, C- s, D- p
  • A- p, B- r, C- q, D- t
  • A- q, B- p,C- t, D- s
  • A- s, B- r, C- t, D- p
The diploid number of human chromosomes was corrected from 48 to 46 by
  • Waldeyer
  • Harris and Watkin
  • Tijo and Levan
  • Beadle and Tatum
If a cross is made between two individuals, each having genotype Bb, two offsprings are obtained. Out of these first has dominant trait. What is the probability that the second offspring will exhibit recessive trait?
  • 1/4
  • 100
  • Zero
  • 3/4
In pedigree analysis symbol $$\bigodot$$ is used for 
  • Heterozygous for autosomal recessive
  • Affected individuals
  • Death
  • Carrier for sex linked recessive
Sex chromosomes were first studied by
  • Mclung 1902
  • Castle 1903
  • Stevens 1905
  • Correns 1905
Which one of the following symbols and its representation, used in human pedigree analysis is correct?
  • $$\Box =$$ unaffected female
  • $$\blacklozenge =$$ male affected
  • $$\bigcirc =$$ unaffected male
In sickle cell anaemia, the glutamic acid is replaced by 
  • Proline
  • Alanine
  • Serine
  • Valine
  • Glycine
Polydactyly in man is due to
  • Autosomal dominant gene
  • Autosomal recessive gene
  • Sex-linked dominant gene
  • Sex-linked recessive gene
Which of these is not a Mendelian disorder?
  • Cystic fibrosis
  • Sickle cell anaemia
  • Colour blindness
  • Turner's syndrome 
  • Hemophilia
The person with Turner's syndrome has 
  • 45 autosomes and X sex chromosome
  • 44 autosomes and XYY sex chromosomes
  • 45 autosomes and XYY sex chromosomes
  • 44 autosomes and X sex chromosome
A family has 9 girls, probability of son at 10th  birth would be _________.
  • 50%
  • 100%
  • 25%
  • 75%
Down's syndrome is an example of 
  • Aneuploidy
  • Polyteny
  • Polyploidy
  • Monoploidy
  • Triploidy
A man can inherit his X chromosome from
  • His maternal grand mother or maternal grand father
  • His father
  • His maternal grand father only
  • His paternal grand father
  • His paternal grand mother
Who proposed the chromosomal theory?
  • Bateson and Punnet
  • Mendel
  • Morgan
  • Sutton and Boveri
One of the following is a mismatch.
  • Down syndrome - Autosomal aneuploidy
  • Klinefelter syndrome - XO complement
  • Haemophilia - Sex linked
  • Turner syndrome - Females with retarted sexual development
What chromosome arrangement is symbolized by 2n+2? 
  • Tetraploid
  • Nullisomic
  • Trisomic
  • Tetrasomic
Mutation was first discovered by
  • Muller
  • Morgan
  • Stadler
  • Hugo de Vries
Individuals with a karyotype of 45 chromosome 44 autosome and one sex chromosome have been found to suffer from an abnormality called as female dysgenesis or
  • Down syndrome
  • Turner syndrome
  • Klinefelter's syndrome
  • Testiculer feminisation
Polyploidy can be produced artificially by
  • Colchicine
  • Inbreeding
  • Line breeding
  • Self pollination
Mutations are generally 
  • Recessive
  • Dominant
  • Harmful
  • All of the above
A person has long legs, female like appearance with breast (gynecomastia) and sterile will have one or the genetic compliment
  • XO
  • XXY
  • XXO
  • XXX
The gene that causes cancer upon mutation is called as
  • Mutagene
  • Oncogene
  • Plasmagene
  • None of the above
Due to non-disjunction of chromosomes during spermatogenesis, sperms carry both sex chromosomes (22A + XY) and some sperms do not carry sex chromosome (22A + 0). If these sperms fertilize normal eggs (22A + X). What types of genetic disorders appear among the offspring ?
  • Down's syndrome and Turner's syndrome
  • Down's syndrome and Cri-du-chat syndrome
  • Turner's syndrome and Klinefelter's syndrome
  • Down's syndrome and Klinefelter's syndrome
To be successful in evolution, a mutation must occur in
  • Plasma proteins
  • Somatoplasmic DNA
  • Germplasm's DNA
  • RNA
Which type of division leads to polyploidy?
  • Cryptomitosis
  • Meiosis
  • Endomitosis
  • Amitosis
Which out of these have genetic complement 44+X?
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  • A
  • B
  • C
  • D
Mutation theory was proposed by
  • Hugo de Vries
  • Gregor Mendel
  • Lamarck
  • Kolreuter
The smallest unit of genetic material which upon mutation produce a phenotypic effect is
  • Muton
  • Inducer 
  • Regulator
  • None of the above
The minimum requirement for mutation is a
  • Change of triplet codon
  • Change in single nucleotide
  • Change in whole DNA
  • Change in single strand of DNA
Which of the following undergoes change in mutation?
  • Chromosome
  • Structure of gene
  • Sequence of gene
  • Any of the above
Which of the following can be called as a mutation?
  • The halfing of the chromosome number at meiosis
  • The doubling of the chromosome after syngamy
  • The possession of an additional chromosome
  • All of the above
Mutations are generally
  • Dominant
  • Recessive
  • Codominant
  • Incompletely dominant
Mutation is 
  • An abrupt or discontinuous change which is inherited
  • A factor for plant growth
  • A change which affects parents only and is never inherited
  • A change which affects the offspring of F$$_2$$ generation
Mostly mutations are
  • Heritable
  • Non-heritable
  • Harmful
  • Beneficial
Mutation normally causes
  • Small changes
  • Negligible changes
  • Large changes
  • All of the above
Haploids are preferred over diploids for mutation studies because
  • Recessive mutation is expressed in F$$_{1}$$.
  • Recessive mutation is expressed in F$$_{2}$$.
  • Dominant phenotype is expressed.
  • Dominant phenotype is suppressed.
Which of the following is a genetic disease?
  • Sickle cell anaemia
  • Tuberculosis
  • Severe Acute Respiratory Syndrome
  • Acquired Immuno Deficiency Syndrome
When a cross is made between two parents with respect to a single character, it is called as
  • Dihybrid
  • Monohybrid
  • Trihybrid
  • None of these
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