Explanation
Hint: One of the prominent symptoms of lead poisoning is sluggishness and fatigue.
Part 1- Poison:The substance which can result in death or harm organs, tissues due to its action is termed as poison. Poisons depending on its chemical component is classified into two types, they are;
Metallic poison
Non-metallic poison
Metallic poison are often slowly eliminated and gets accumulated in the body.
Part 2- Lead poisoning:Lead [Pb (plumbum)] is a heavy metal. They are the main constituent of paint, industrial dust and effluents and also gasoline products. This metallic poison often on exposure poses a great threat to health. The symptoms of lead poisoning are vomiting, breathlessness, fatigue, abdominal pain, anemia, etc.
Part 3- Action of lead on hemoglobin:The chronic exposure to lead poses risk to the process of formation of hemoglobin. It inhibits the ability to produce hemoglobin by disrupting the steps in the heme synthesis pathway, which ultimately decreases the hemoglobin content and thereby causing anemia.
Part 4- Conclusion: Hemoglobin is an oxygen carrier molecule present in red blood cells. Lead poisoning affects the synthesis of hemoglobin, thereby reducing its oxygen carrying capacity.
Final Step: Lead poisoning affects the oxygen carrying capacity of blood cell as it affects the heme-synthesis pathway.
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