Explanation
The discovery of __________ proved that atom is divisible.
Physical stuck to pure 16O for mass scale and chemistry used an average of all three isotopes because natural oxygen is the mixture of 16O, 17O and 18O. There was not much difference on average.
But with molecules of 200-500 amu, it starts to add up. Use of 12C which is isotopically pure, get narrow down the difference between physical and chemical atomic masses.
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