Human insulin is being commercially produced from a transgenic species of

  • Escherichia

  • Mycobacterium

  • Rhizobium

  • Saccharomyces

Cry-I endotoxins obtained from Bacillus thuringiensis are effective against

  • mosquitoes                         

  • Nematodes
  • boll worms                         
  • Flies

What is an antisense technology?

  • A cell displaying a foreign antigen used for synthesis of antigens.

  • Production of somaclonal variants in tissue cultures.

  • When a piece of RNA that is complementry in sequence is used to stop expression of a specific gene

  • RNA polymerase producing DNA

The foreign gene in a transgenic plant may be derived from

 

  • an insect 

  • an animal

  • a bacteria 

  • all of these.

Cultivation of Bt cotton has been much in the news. The prefix Bt means

  • "Barium-treated" cotton seeds

  • "Bigger thread" variety of cotton with better tensile strength

  • produced by "biotechnology" using restriction enzymes and ligases

  • carrying an endotoxin gene from Bacillus thuringienesis.

An example of gene therapy is 

  • production of injectable hepatitis B vaccine 

  • production of vaccines in food crops like potatoes which can be eaten

  • introduction of gene for adenosine deaminase in persons suffering from Severe Combined Immuno-deficiency (SCID)

  • production of test tube babies by artificial insemination and implantation of fertilized eggs.

Which onc of the following is a correct statement?

  • "B" in "Bt-cotton" indicates that it is a genetically modified organism produced through biotechnology

  • Somatic hybridization involves fusion of two complete plant cells carrying desired genes.

  • The anticoagulant hirudin is being produced from transgenic Brassica napus seeds.

  • "Flavr Savr" variety of tomato has enhan the production of ethylene which improves its taste.

In transgenics, expression of transgene in target tissue is determined by

  • enhancer

  • transgene

  • promoter

  • reporter

Eugenics is the branch concerned with


 

  • improving the quality of human race by symptomatic treatment of genetic diseases.

  • improving the quality of human populations by the application of genetic principles.

  • improving the quality of human race by providing best suitable environment.

  • none of the above.

Which of following cartoon characters does not share its name with that of a gene?

  • Tintin

  • Popeye

  • Asterix

  • Obelix

RNA interference is essential for the

  • cell proliferation

  • cell defence

  • cell differentiation

  • micropropagation

Genetically modified (GM) crops can be produced by

  • recombinant DNA technology

  • somatic hybridization

  • cross breeding

  • micropropagation

Which of the following genes do not occur naturally in living organisms?

  • Bt genes

  • RNAi genes

  • Cry genes

  • Endogeneous cytoplasmic defense genes

Adenosine deaminase (ADA deficiency) could be permanently cure, if the gene isolated from marrow cells producing ADA is introduced into cell at

  • early embryonic stages

  • Late embryonic stages

  • early childhood

  • None of the above

The first clinical gene therapy was given for treating

  • diabetes mellitus

  • chickenpox

  • rheumatoid arthritis

  • adenosine deaminase deficiency

The protein products of the  following Bt toxin genes cry I Ac and cry II Ab are responsible for controlling

  • bollworm

  • roundworm

  • moth

  • fruit fly

Three critical research areas of biotechnology are:

I. Providing the best catalyst in the form of improved organism usually a microbe or pure enzyme

II. Multiple Ovulation Transfer Technology (MOET)

III. Creating optimal conditions through engineering for a catalyst to act.

IV. Downstream processing technologies

  • I, II, III, IV      

  • I, III, IV          

  • I, II                 

  • II and IV

Bt toxin is: 

  • Intracellular lipids                      

  • Intracellular crystalline protein

  • Extracellular crystalline protein    

  • Intracellular polysaccharide

Bt toxin is harmful to insects like:

  • Lepidoterans (tobacco budworm, armyworms)

  • Coleopterans (bettles)

  • Dipterans (flies and mosquito)

  • All are correct

Antisense RNA is:

  • RNA that makes opposite sense

  • RNA that investigators find confusing

  • The non-coding strand of DNA molecule

  • RNA that is complementary to certain mRNA

Which of the following statements is false?

I. Insulin was originally extracted from pancreas of slaughtered pigs and cattle

II. Animal insulin is difficult to obtain

III. Animal insulin is identical to human insulin

IV. Non human insulin caused some patients to develop allergy

V. Recombinant DNA allowed scientists to insert a human insulin gene into a bacterial expression vector

VI. Recombinant insulin is actually obtained from E. coli bacterial cell

  • Only I and II

  • Only III and IV

  • Only III

  • Only VI

Which step proved to be the main challenging obstacle in the production of human insulin by genetic engineering? 

  • Splitting A and B polypeptide chains

  • Addition of C-peptide to pro-insulin

  • Getting insulin assembled into mature form

  • Removal of C-peptide from active insulin

Which technique would you expect to be completely curative in SCID?

  • Gene therapy in adult stage

  • Gene therapy in embryonic stage

  • Bone marrow transplantation

  • Enzyme replacement therapy

For effective treatment of a disease: 

  • Early diagnosis is needed but understanding of its pathophysiology is not needed

  • Early diagnosis is not needed but understanding of its pathophysiology is needed

  • Early diagnosis and understanding of its pathophysiology are needed

  • Neither early diagnosis nor understanding of its pathophysiology is needed

"Rosie" a transgenic cow known to produce a type of milk which has all the following characteristics except: 

  • Protein content of 2.4 gm/litre

  • Has human α-lactalbumin

  • More balance diet than normal milk for babies

  • None of these

Which of the following is correct?

  • The procedure for chemical safety testing / toxicity is the same as that used for testing toxicity of drugs

  • Transgenic animals are more sensitive to the toxic substances than non-transgenic animals

  •   Golden rice, a genetically engineered rice has high vitamin A (β-carotene) content

  • All are correct

Introduction of genetically modified food is not desirable because: 

  • Allergies and toxicity may be caused

  • Incorporation of antibiotic resistance in human beings

  • Disturbance in metabolism due to enzyme for antibiotic resistance 

  • All are correct

The use of bioresources by multinational companies and other organizations without proper authorization from the countries and people concerned without compensatory payment is called:

  • Bioethics

  • Biopiracy

  • Bioterror

  • Bioweapon

Which of the following is / are product(s) of genetic engineering:

A. Humulin

B. Hepatitis B vaccine prepared by yeast

C. Golden rice

D. Bt cotton

  • A, B

  • B, C

  • A, B, C

  • A, B, C, D

Which is incorrect? 

  • Specific Bt toxin genes have been isolated from Bacillus thuringiensis. 

  • Meloidegyne incognitia does not infect the roots of tobacco plants

  • In mammals insulin is synthesized as a prohormone

  • ADA deficiency can be cured by bone marrow transplantation

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Practice Zoology Quiz Questions and Answers