The choice of Bt toxin gene depends on
Crop
Targeted pest
Both A and B
Only on protein of Bt toxin gene
Most of the Bt toxin genes are
Insect group specific
Pest specific
Weed specific
Bacteria specific
The Bt toxin is not coded by
CrylAc
CryllAb
CrylAb
CrylIIAc
Cotton bollworms are controlled by
CryIAc
Cry II Ab
Cry I Ab
Corn borers are controlled by
CryIAb
CryIIAb
Both B and C
The tobacco roots are infected by
Nematode Meloidegyne incognitia
Diptera beetles
Coleoptera fly
Lepidopterans
Silencing of specific mRNA due to a complementary dsRNA is called mRNA silencing. Here the source of ds RNA is
RNA virus
Mobile genetic element with RNA intermediate
Transposons having RNA intermediate during process of replication
All of these
Agrobacterium vectors carried nematode specific genes which is introduced into the host plant and suct that it produced
Sense and anti sense RNA
Only antisense RNA
Only sense RNA
Sense and antisense Protein
According to NCERT data how many recombinant therapeutics have been approved for human use and how many are marketed in India?
12, 6
32, 16
30, 12
12, 10
How many chains does proinsulin consist of?
Three
Two
One
Five
Which of the following peptides is present in only proinsulin not in insulin?
A
B
C
Both A and C
The main challenge for the production of insulin using r-DNA technologies was
Getting insulin assembled into a mature form
Getting insulin from human source
Getting insulin synthesized chemically in proinsulin form
Getting C peptide synthesized.
An American company which synthesized the DNA sequences for insulin was
Eli lity
Eili Lily
Ele Lily
Eli Lilly
For the first time, the synthesis of two DNA sequences of insulin was carried out by Eli Lilly in
1972
1981
1983
1987
Insulin chains produced by Eli Lilly using recombinant DNA technology, actually taken which of the following strain of bacteria?
Escherichia coli
Bacillus subtilis
Saccharomyces cerevisiae
Bacillus xenus
Gene therapy is not
An attempt to correct a gene defect
By which genes are inserted into an individual or embryo to take over the function of and compensate the non-functional gene.
Genes are inserted into a person's cells and tissues to treat a disease
Correction of environmental defect by inserting a gene
Which of the following is not correct about the first clinical gene therapy?
1990 year
5 year old kid
Adenosine deamide deficiency
The ADA deficiency is because of
Substitution
Inversion
Deletion
Insertion
The possible treatments of ADA deficiency are
Bone Marrow Transplantation
Enzyme replacement Therapy
Both
None of these
Which of the following therapies for ADA deficiency are not completely curative?
Both are completely curative
The first step of gene therapy would be
Culture of the lymphocytes from patient's blood
Using vector for transmitting gene
cDNA was prepared
cDNA was inserted directly into the cells
The last step of gene therapy would be
The corrected lymphocytes are returned to the patients
Culture of lymphocytes of the patient
Introduction of correct gene in cultured cells
Removal of corrected lymphocytes from culture
The permanent cure of gene therapy can be
Cells isolated from bone marrow in an adult were cultured and transformed with corrected gene
Cells isolated from thymus in an adult were cultured and transformed with corrected gene
Cells isolated from bone marrow in an embryo were cultured and transformed with corrected gene
Genes isolated from bone marrow were introduced into the cells at early embryonic stage
Conventional methods are not
Serum analysis
Urine analysis
For early detection
Early diagnosis of a disease cannot be served by
ELISA
PCR
Recombinant DNA Technology
X-Ray
PCR will allow to detect genetic defects but doesn't involve which of the following steps.
Probing with radioactive molecule
Hybridization
Autoradiography
Antigen antibody interaction
ELISA involves
Detection by the presence of antigens
Detection by the presence of antibodies synthesized against pathogen
Only detection of the outer coat of pathogen
Transgenic animals are
The ones with manipulated proteins
The ones with manipulated DNA
The ones with manipulated mRNA
The ones with manipulated efficiency
Transgenic animals:
All are mice
More than 95% are mice
More than 90% are mice
95% are mice
Transgenic animals are created not to study which of the following options
The regulation of genes
Study of disease
For biological products
Diagnostics
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