In India, the organization responsible for assessing the safety of introducing genetically modified Organisms for public use is
  • Indian Council of Medical Research (ICMR)

  • Council for Scientific and Industrial Research (CSIR)
  • Research Committee on Genetic Manipulation (RCGM)
  • Genetic Engineering Appraisal Committee (GEAC)

A 'new variety of rice was patented by a foreign company though such varieties have been present in India for a long time. This is related to

  • Co-667

  • Sharbati Sonora

  • Lerma Rojo

  • Basmati

Use of bioresources by multinational companies and organizations without authorization from the 
concerned country and its people is called

  • Bio-infringement
  • Biopiracy
  • Biodegradation
  • Bioexploitation

The first human hormone produced by recombinant DNA technology is :

  • Insulin

  • Estrogen

  • Thyroxin

  • Progesterone

Which of the following Bt crops is being grown in India by the farmers?

  • Cotton

  • Brinjal

  • Soybean

  • Maize

Consumption of which one of the following foods can prevent the kind of blindness associated with vitamin-A deficiency?

  • Flaver savr tomato

  • Canolla

  • Golden rice

  • Bt-brinjal

Transgenic plants are

  • produced by a somatic embryo in artificial medium

  • generated by introducing foreign DNA into a cell and regenerating a plant from that cell

  • Produced after protoplast fusion in artificial medium

  • grown in artificial medium after hybridization in the field

Golden rice is a promising transgenic crop. When released for cultivation, it will help in:

  • alleviation of vitamin-A deficiency

  • pest resistance

  • herbicide tolerance

  • producing a petrol-like fuel from rice

Which of the following is true for Golden rice?

  • It has yellow grains, because of gene introduced from a primitive variety of rice

  • It is Vitamin A enriched, with a gene from daffodil

  • It is pest resistant, with a gene from Bacillus thuringiensis

  • It is drought tolerant, developed using Agrobacterium vector

Why does Bt toxin not kill Bacillus thuringiensis?

  • The bacillus keeps proteins in inclusions
  • The toxin exists in the bacillus as a pro-toxin
  • The bacillus protects its genetic material by methylation
  • The bacillus has a tough cell wall of peptidoglycan

Cotton plants can be protected from corn borer by the proteins coded by:

  • cryIAc                       
  • cryIIAb
  • cryIAb                       
  • cryIAd

RNAi, as a mechanism of cellular defense, takes place in:

  • All bacteria

  • All unicellular organisms

  • All plants only

  • All eukaryotic organisms

How were nematode specific genes introduced in tobacco plant?

  • Using page DNA

  • Using a retrovirus

  • By gene gun

  • Using Agrobacterium tumefaciens

The first clinical gene therapy trial was given in 1990 to a 4 year girl with:

  • Alpha – 1 antitrypsin deficiency

  • Cystic fibrosis

  • Adenosine deaminase deficiency

  • Chronic myeloid leukemia

Over 95 % of all transgenic animals are:

  • Mice

  • Pigs

  • Sheep

  • Rabbits

The transgenic cow, Rosie, produced milk that:

  • Contained human beta lactalbumin

  • Interferons to treat viral infections

  • Alpha – 1 antirypsin

  • Is protein enriched

Match each item in Column I with one in Column II and select the answer from the codes given below:

 

COLUMN I

 

COULMN II

A

Bioprospecting

a

the process of discovery and commercialization of new products based on biological resources

B

Biopiracy

b

the exploitative patenting of already widely used natural resources, such as plant varieties, by commercial entities

C

Bioremediation

c

a process that uses microorganisms or their enzymes to treat polluted sites for regaining their original condition

D

Biofortification

d

the process by which the nutritional quality of food crops is improved through agronomic practices, conventional plant breeding, or modern biotechnology

Codes
    A    B    C    D

  •   a    b    c    d
  •   a    b    d    c
  •   b    a    c    d
  •   b    a    d    c

Bt cotton variety that was developed by the introduction of toxin gene of Bacillus thuringiensis (BT) is resistant to

  • Fungal diseases

  • Plant nematodes

  • Insect predators

  • Insect pests

Match the organism with its use in biotechnology.

(a) Bacillus thuringiensis                (i) Cloning vector

(b) Thermus aquaticus                   (ii) Construction of first rDNA molecule

(c) Agrobacterium tumefaciens      (iii) DNA polymerase

(d) Salmonella typhimurium           (iv) Cry proteins

Select the correct option from the following:

    (a)   (b)   (c)   (d)

  • (iv)  (iii)   (i)    (ii)

  • (iii)  (ii)   (iv)   (i)

  • (iii)  (iv)  (i)    (ii)

  • (ii)  (iv)  (iii)   (i)

Match the following columns and select the correct option.

    Column - I          Column - II

a. Bt cotton           (i) Gene therapy

b. Adenosine        (ii) Cellular defence
    deaminase
    deficiency

c. RNAi                (iii) Detection of HIV infection

d. PCR                  (iv) Bacillus thuringiensis

    (a)  (b)  (c)  (d)

  • (iii)  (ii)   (i)  (iv)

  •  (ii)  (iii)  (iv)  (i)

  •  (i)   (ii)   (iii)  (iv)

  •  (iv)  (i)   (ii)  (iii)

RNA interference is used for which of the following purposes in the field of biotechnology?

  • to develop a plant tolerant to abiotic stresses

  • to develop a pest-resistant plant against infestation by nematode

  • to enhance the mineral usage by the plant

  • to reduce post-harvest losses

The laws and rules to prevent unauthorized exploitation of bio-resources are termed as -

  • Biopatenting

  • Bioethics

  • Bioengineering

  • Biopiracy

Which of the following is not an application of PCR (Polymerase Chain Reaction)?

  • Purification of isolated protein

  • Detection of gene mutation

  • Molecular diagnosis

  • Gene amplification

When gene targetting involving gene amplification is attempted in an individual's tissue to treat disease, it is known as:

  • Molecular diagnosis

  • Safety testing

  • Biopiracy

  • Gene therapy

Nowadays, it is possible to detect the mutated gene causing cancer by allowing the radioactive probe to hybridise its complementary DNA in clone of cells, followed by its detection using autoradiography because:

  • mutated gene does not appear on a photographic film as the probe has no complementarity with it.

  • mutated gene does not appear on a photographic film as the probe has complementarity with it. 

  • mutated gene partially appears on a photographic film.

  • mutated gene completely and clearly appears on a photographic film.

With regard to insulin, choose the correct options :

a. C-peptide is not present in mature insulin.

b. The insulin produced by rDNA technology has C-peptide.

c. The pro-insulin has C-peptide.

d. A-peptide and B-peptide of insulin are interconnected by disulphide bridges.

Choose the correct answer from the options given below.

  • (a), (c) and (d) only

  • (a) and (d) Only

  • (b) and (d) only

  • (b) and (c) only

For effective treatment of the disease, early diagnosis and understanding its pathophysiology is very important. Which of the following molecular diagnostic techniques is very useful for early detection?

  • ELISA Technique

  • Hybridization Technique

  • Western Blotting Technique

  • Southern Blotting Technique

The Adenosine deaminase deficiency results into:

  • Digestive disorder 

  • Addison's disease

  • Dysfunction of Immune system

  • Parkinson's disease

Golden rice has been produced by:
 
  • Cross hybridisation with wild varieties
  • Transforming rice by genetic engineering
  • Mutation breeding
  • Somatic hybridisation
Which of the following is probably the most economically important plant-parasitic nematode species among the tropical and subtropical regions?
 
  • Meloidogyne incognita
  • Coenorhabditis elegans
  • Heterodera glycines
  • Arthrobotrys dactyloides
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