The biggest advantage of growing Bt cotton instead of non-Bt varieties is:
 
  • reductions in pesticides to be sprayed on a crop and the ecological benefits which stem from that.
  • increased yield of cotton due to effective control of three types of bollworms
  • Reduction in predators which help in controlling the bollworms by feeding on larvae and eggs of bollworm
  • Potential reduction in the cost of cultivation
Flavr Savr, a GM tomato, has been developed for:
 
  • Insect resistance
  • Increased shelf life
  • Herbicide resistance
  • Increased vitamin A content
In 1995, the European Patent Office wrongly granted a patent on an anti-fungal product derived from Azadirachta indica to the US Department of Agriculture and W. R. Grace and Company. The common name of this plant in India is:
 
  •     Haldi
  •     Neem
  •     Basmati
  •     Arjun
The first licensed drug generated using recombinant DNA technology was:
 
  •     Human growth hormone
  •     Human insulin
  •     Tissue plasminogen activator
  •     Factor VIII
The main challenge for production of insulin using rDNA techniques was:
 
  • getting insulin assembled into a mature form. 
  • isolating DNA in pure form from human cell
  • selecting the vector for cloning the gene
  • purification of the human insulin
The first transgenic cow produced:
 
  • enzyme to treat emphysema
  • human protein enriched milk
  • enzyme to treat phenylketonuria
  • organs for xenotransplantation
Biopiracy is:
  • the exploration of natural sources for small molecules, macromolecules and biochemical and genetic information that could be developed into commercially valuable products.
  • exploitation of a region's biological resources or indigenous knowledge unethically and without providing fair compensation.
  • the use of living organisms, like microbes and bacteria, in the removal of contaminants, pollutants, and toxins from soil, water, and other environments
  • the process of developing a crop with bioavailable micronutrients in its edible parts.
Consider the given two statements:
I. The first clinical gene therapy was given to a girl with adenosine deaminase deficiency
II. The first recombinant therapeutic product approved for human use was Human Insulin
 
  • Only I is correct
  • Only II is correct
  • Both I and II are correct
  • Both I and II are incorrect
India successfully protected itself against biopiracy in a case where in late 1997, the United States Patent and Trademark Office granted a patent to:
  • Co-667
  • Sharbati Sonora
  • Lerma Rojo
  • Basmati
ELISA works on the principle of:
 
  • antigen-antibody interaction
  • radioactive probe tagging
  • culture of microbe in an artificial medium
  • histopathology
Identify the incorrect statement regarding Bacillus thuringiensis?
 
  • forms protein crystals during a particular phase of their growth which contains a toxic insecticidal protein.
  • The Bt toxin protein exists as inactive protoxin that is converted into an active form by an alkaline pH in the insect's gut
  • Activated toxin binds to the surface of midgut epithelial cells, create pores,  causes cell swelling and lysis and eventually death of the insect.
  • Proteins encoded by the genes cryIAc and cryIIAb control the corn borer, that of cryIAb controls cotton bollworms.
RNA interference:
I. involves silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA (silencing).
II. has been used to create transgenic tobacco plants resistant to nematode Meloidogyne incognitia
  • Only I is correct
  • Only II is correct
  • Both I and II are correct
  • Both I and II are incorrect
To produce human recombinant insulin Eli Lily:
 
  • prepared two DNA sequences corresponding to A and B chains of human insulin and introduced them in plasmids of E. coli to produce insulin chains.
  • prepared two DNA sequences corresponding to A and C chains of human insulin and introduced them in plasmids of Yeast to produce insulin chains.
  • used reverse transcription of the hnRNA transcript of insulin gene to make complementary DNA.
  • used fragments created by restriction enzyme digestion to isolate and used the gene for insulin from pancreatic cells.
Which of the following can permanently cure ADA deficiency?
 
  • Bone marrow transplant
  • Enzyme replacement therapy
  • Introduction of the gene isolated from marrow cells producing ADA at early embryonic stages.
  • Introduction of a functional ADA cDNA (using a retroviral vector) into peripheral lymphocytes.
Identify the incorrect statement regarding transgenic animals?
 
  • α-1 antitrypsin is being produced in a transgenic sheep
  • The first transgenic cow, Rosie, produced human protein-enriched milk (2.4 grams per litre).
  • Transgenic mice are being used to test the safety of the polio vaccine.
  • Over 95 percent of all existing transgenic animals are cattle.
GEAC stands for:
 
  • Genetic Engineering Approval Committee  
  • Green Environment Action Committee
  • Genetic Engineering Appraisal Council
  • Genetic Ethics Approval Committee

The term used to refer to the use of bio-resources by multinational companies and other organisations without proper authorisation from the countries and people concerned without compensatory payment is:
  • Bioprospecting
  • Biopiracy
  • Biomagnification
  • Bioaccumulation

Identify the incorrectly matched pair:
1. Golden rice Vitamin B12 enriched rice
2. Rosie First transgenic cow
3. Bt Cotton Genetically modified pest resistant plant cotton variety
4. Basmati controversy Biopiracy
  • 1
  • 2
  • 3
  • 4
A chronic respiratory disorder, commonly caused by cigarette smoking but rarely due to deficiency of α-1 antitrypsin enzyme, is
 
  • Bronchial asthma
  • Tuberculosis
  • Emphysema
  • Pneumoconiosis
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