Distance between two consecutive nucleotide pairs of DNA is

  • 0.34nm

  • 34angstrom

  • 3.4 micrometre

  • 34nm

The major approaches used in HGP for identifying genes were

  • BLAST

  • Expressed Sequence Tags

  • Sequence annotation

  • b and c

Which of the following were not used in HGP?

  • Vectors like BAC and YAC

  • Hosts like plants and animals

  • Protein sequencers

  • DNA sequencers

Frederick Sanger is credited for the invention of

  • DNA sequencing method

  • Protein sequencing method

  • Both

  • RNA sequencing method

The last chromosome to be sequenced in HGP was

  • the last chromosome of the human genome

  • the first chromosome of the human genome

  • chromosome I

  • Both b and c

In a 3.2 Kbp long piece of DNA, 820 adenine bases were found. What would be the number of cytosine bases?

  • 780

  • 1560

  • 740

  • 1480

James Watson and Francis Crick got Nobel prize in the year

  • 1960

  • 1962

  • 1959

  • 1953

Polymerisation of which of the following produces Nucleic acids?

  • Nucleosides

  • Nucleotides

  • DNA and RNA

  • Both 1 and 2

Which of the following is a genetic material in most of the organisms?

  • DNA

  • RNA

  • Both DNA and RNA

  • Nucleic Acid

Which of the following can act as genetic material?

  • RNA only

  • DNA only

  • DNA but not RNA

  • DNA and RNA

RNA cannot act as

  • Adapter molecule

  • Catalytic molecule

  • Respiratory substrate

  • Genetic material

RNA can act as

  • Adapter molecule

  • Catalytic molecule as well as Genetic material

  • Structural molecule

  • All of the above

How many types of nucleic acids are found in the living system?

  • 1

  • 2

  • 4

  • 3

The new era of genomics started with the determination of

  • human genome sequence

  • bacteria genome sequence

  • discovery of PCR

  • protein sequencing

The most interesting molecule in the living system is

  • the most abundant genetic material

  • the genetic material in most of the organisms

  • the long polymer of deoxyribonucleotides

  • all of the above

During portein synthesis in an organism at one point the process comes to a halt. Select the group of the three codons from the following, from which any one of the three colud bring about this halt.

  • UUU, UCC, UAU

  • UUC, UUA, UAC

  • UAG, UGA, UAA

  • UUG, UCA, UCG

Which organism has more base pairs ?

  • E.coli

  • Bacteriophage

  • human

  • Yeast

What is incorrect about the following figure representing DNA replication?

  • The direction of DNA replication in strand (i).

  • The direction of DNA replication in strand (ii).

  • Discontinuous replication of strand (i)

  • Discontinuous replication of strand (ii).

The binding site of tRNA with mRNA & amino acids respectively are

  • mRNA with DHU loop and amino acid with CCA end.

  • mRNA with CCA end and amino acid with anticodon loop.

  • mRNA with anticodon loop and amino acid with DHU loop.

  • mRNA with anticodon loop and amino acid with CCA end.

Which of the following is correct regarding genetic code?

  • UUU is the initiation codon which also codes for phenylalanine.

  • There are 64 triplet codons and only 20 amino acids.

  • Three random nitrogen bases specify the placement of one amino acid.

  • UAA is the nonsense codon which also codes for methionine.

Which of the following set of options is used in translation?

  • hnRNA, tRNA, rRNA

  • mRNA, tRNA, rRNA

  • mRNA, tRNA, hnRNA

  • hnRNA, rRNA, tRNA

Which of the following rRNAs act as structral RNA as well as ribozyme in bacteria ?

 

  • 5 srRNA

  • 18 srRNA

  • 23 srRNA

  •   58 srRNA

DNA-dependent RNA polymerase catalyses transcription on one strand of the DNA which is called the 

  • template strand

  • coding strand

  • alpha strand

  • anti strand

Which of the following is not required for any of the techniques of DNA fingerprinting available at present ?

  • Zinc finger analysis

  • Restriction enzymes

  • DNA-DNA hybridisation

  • Polymerase chain reaction

Which one of the following is the start codon?

  • UGA

  • UAA

  • UAG

  • AUG

In eukaryotes which of the following is removed from initially transcribed RNA before it is transported to the cytoplasm for translation ?

  • Intron

  • 3' Poly A tail

  • Ribosome binding site

  • 5' cap

The process of splicing in eukaryotes :

  • is reminiscent of antiquity 

  • represents dominance of RNA world

  • is an indicator of the complexity of human genome

  • is a legacy of organic evolution

In prokaryotes, the predominant site for control of gene expression is the  :

  • transcription initiation 

  • processing level

  • transport of mRNA 

  • translation level

In Hershey and Chase experiment, what finding led to the conclusion that DNA is the genetic material ?

  • The presence of radioactivity in the bacteria when 35S was used.

  • The presence of radioactivity in the supernatant when 35S was used.

  • The presence of radioactivity in the bacteria when 32P was used.

  • The presence of radioactivity in the supernatant when 32P was used.

Which of the following important biochemical reactions in living systems is catalyzed by a ribozyme?

  • Repair of DNA

  • Electron transport chain

  • Formation of peptide bond

  • Organization of MTOC during cell division

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