In human child, sex is determined by

  • Size and number of sperms in semen

  • Size of egg to be fertilized

  • Sex chromosomes of father

  • 4. Sex chromosomes of mother

Round seed trait (R) is dominant over wrinkled (r) seed trait in Pea. Heterozygous round seeded plant (Rr) is crossed with wrinkled seed plant (rr). What is the possible progeny?

  • 302 round : 102 wrinkled

  • 210 round : 95 wrinkled

  • 103 round : 99 wrinkled

  •  103 round : 315 wrinkled

A dihybrid cross produces the following progeny - AaBb = 240; Aabb =754; aaBb = 746; aabb = 260. What is the distance between the two genes on the chromosome?

  • 12.5 map units

  • 1 map unit

  • 20 map units

  • 25 map units

Male pattern baldness is a          trait

  • sex-linked

  • sex-limited

  • sex-influenced

  • Y-linked

A colour blind girl is rare because she will be born only when 

  • Her mother and maternal grand father were colour blind

  • Her father and maternal grand father were colour blind

  • Her mother is colour blind and father has normal vision

  • Parents have normal vision but grand parents were colour blind. 

Identify the incorrect statement regarding experiments on Pisum sativum by Gregor Mendel?

  • He conducted hybridisation experiments on garden peas for seven years (1856-1863) and proposed the laws of inheritance in living organisms.

  • It was for the first time that statical analysis and mathematical logic were applied to problems in biology.

  • Unfortunately his experiments had a small sampling size, which gave less credibility to the data that he collected.

  • He investigated characters in the garden pea plant that were manifested as two opposing traits. 

Which of the following is a recessive trait for a character choosen by Mendel in garden pea?

  • Violet flower color

  • Yellow pod color

  • Axial flower position

  • Tall stem height

Indentify the incorrect statement:

 

  • Tall plant produce gametes by meiosis and the dwarf plants by mitosis.

  • Only one allele is transmitted to a gamete.

  • The segregation of alleles is a random process.

  • Gametes will always be pure for the trait.

The ultimate source of allelic variation is:

  • Recombination

  • Natural selection

  • Mutation

  • Drift

In the case of co-dominance, the F1 generation resembles:

  • Dominant parent

  • Recessive parent

  • Both the parents

  • None of the parents

What can be the possible blood groups of progeny whose father and mother are of A and B group respectively?

  • A and B only

  • AB only

  • All except O

  • A, B, AB and O

When Morgan hybridised yellow-bodied, white-eyed females to brown-bodied, red-eyed males and intercrossed their F1 progeny, the F2 ratio deviated very significantly from the 9:3:3:1 ratio. this can be attributed to the fact that:

  • The genes are located on X and Y chromosomes

  • Fruit fly has abnormal chromosomes

  • The genes are located on the X chromosome

  • The genes exhibit incomplete dominance

What is incorrect for Hemophilia?

  • In this disease, a single protein that is a part of the cascade of proteins involved in the clotting of blood is affected.

  • In an affected indlvidual a simple cut will result in non-stop bleeding.

  • The heterozygous female (carrier) for haemophilia may transmit the disease to sons.

  • The possibility of a female becoming a haemophilic is extremely rare because mother of such a female has to be hemophilic and the father should be a carrier.

Sickle cell anaemia results from.

  • A chromosomal aberration

  • Non disjunction of autosome

  • A point mutation

  • Blood transfusion reaction

What is the mode of inheritance of phenylketonuria?

  • Autosomal recessive

  • Autosomal dominant

  • Sex linked recessive

  • Sex linked dominant

Failure of cytokinesis after telophase stage of cell divislon results in an increase in a whole set of chromosomes in an organism and, this phenomenon is known as:

  • Aneuploidy

  • Translocation

  • Polyploidy.

  • Inversion

Which of the following is not a feature of Down's Syndrome?

  • It is caused by a non-disjunction in an autosome

  • The affected individual has trisomy of chromosome 21

  • The aflected individual has a characteristic simian palmar crease

  • The mental development of affected individual is normal

Identify the incorrect statement:

 

  • In addition to recombination, mutation is another phenomeonon that leads to variation in DNA.

  • Chromosomal aberrations are commonly observed in cancer cells.

  • A classical example of a point mutation is sickle cell anaemia.

  • Non ionising radiations cannot be mutations. 

Pedigree analysis is resorted to for genetic analysis in humans rather than conventional genetic methods because:

I. Choice matings are not possible

II. Number of progeny is limited

Of the two statements:

  • Only I is correct

  • Only II is correct

  • Both I and II are correct

  • Both I and II are incorrect

Match each item in Column I with one item in Column II and chose your answer from the codes given below:

Column I

Disorder

Column II

Feature

I. Phenylketonuria

II. Sickle Cell anemia

III. Down's Syndrome

IV. Turner's Syndrome

(i) Rudimentary ovaries

(ii) Gynecomastia

(iii) Trisomy 21

(iv) Lack of enzyme PAH

(v) Lack of tyrosinase

(vi) Mutation GAG to GUG

(vii) Mutation GUG to GAG

 

  • I - v; II - vii; III - iii; IV - i

  • I - iv; II - vi; III - iii; IV - i

  • I - v; II - vi; III - iii; IV - ii

  • I - v; II - vi; III - iii; IV - i

In a monohybrid cross F1 progeny resemble neither of the parents. What would be true in this case?

  • The parental traits would not appear in any of the F2 -progenies

  • The F2 phenotypic ratio will be different from the F2 genotypic ratio

  • It could be a case of incomplete dominance

  • The F2 phenotypic ratio will be similar to any Mendelian monohybrid cross

The two alleles of a gene pair are located on:

  • Homologous sites on homologous chromosomes

  • Heterologous sites on homologous chromosomes

  • Homologous sites on heterologous chromosomes

  • Heterologous sites on heretologous chromosomes

Male heterogamety is not seen in:

  • Humans

  • Melandrium album

  • Birds

  • Fruit fly

Aneuploidy results from :

  • Point mutations

  • Gross structural changes in chromosomes

  • Failure of cytokinesis after telophase stage of cell division

  • Failure of segregation of chromatids during cell division 

Which of the following are correct regarding linked genes?

I. are located near each other on the same chromosome.

II. violate the law of independent assortment

III. segregate together during meiosis

  • Only I and II

  • Only I and III

  • Only II and III

  • I, II, III

Consider the cross AaBb x AaBb. If the alleles for both genes exhibit complete dominance, what genotypic ratio is expected in the resulting offspring?

  • 1:1:1:1

  • 9:3:3:1

  • 3:6:3:1:2:1

  • 1:2:1:2:4:2:1:2:1

Two phenotypically normal individuals have an affected child. What can we conclude about the parents?

  • they both carried the diesease allele

  • they are not the parents of the child

  • they are affected

  • no conclusions can be drawn

What is the basis of pleiotropy?

  • A spontaneous mutation during the replication of DNA.

  • Interrelationship between various metabolic pathways in the body.

  • Chromosomal aberration as chromosomes are the vehicles of genes.

  • the behaviour of chromosomes during meiosis or gamete formation.

A female whose father was colorblind marries and normal male whose father was also colorblind. What is the probablility that their daughter will be colorblind?

  • 0 %

  • 25 %

  • 50 %

  • 75 %

In humans, the dominance relationship between the A and B alleles of ABO blood group gene is an example of

 

  • complete dominance.

  • incomplete dominance.

  • codominance.

  • epistasis

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