tRNA looks like
clover-leaf
L shaped
inverted L shaped
a and c
The genetic make up of an organism is determined by
sequences of bases in RNA
sequence of bases in DNA
sequences of amino acids in proteins
all of these
HGP(Human Genome Project) gave a new area in biology called as
BioSciences
Bioinformatics
Biochemistry
Biological sciences
Which of the following was not the goal of Human Genome Project
Identification of human genes
human genome sequence determination
store information in databases
Improve manpower for data analysis
The Human Genome Project started in ______and completed, in__________ year respectively.
1990, 2003
1993, 2003
1993, 2006
1990, 2006
How many of the following were the features of the Human Genome
1. 99.9% bases are present are exactly same in all humans
2. all sequences were found to be coding sequences
3. Repeated sequences make up very large portion of the human genome
4. Repeated sequences are useful for chromosome structure, dynamics and evolution
5. The maximum no of genes were found to be present at the chromosome which was last sequenced
6. The fewest no of genes were found to be present at the chromosome which is present in male only.
1
2
3
5
The locations in human genome which differ by a single base difference is known as
Single nucleotide mutation
Single nucleotide polymorphism
RFLP
Single nucleotide polymorphogenesis
The largest known human gene is
Dystrophin protein gene on X chromosome
Sry gene on Y chromosome
Dystropin protein gene on Y chromosome
Sry gene on X chromosome
If an E.coli with heavy DNA allow to grow for 80 minutes in a culture medium of 14 NH 4
Cl, then what would be the proportion of heavy,light and hybrid densities DNA molecule
respectively?
1/16 : 1/16 : 14/16
0/16 : 14/16 : 2/16
1/16 : 14/16 : 1/16
1/8 : 2/8 : 6/8
Alec Jeffrey’s name is associated with
. DNA sequencing
. DNA fingerprinting
. RNA sequencing
. Gene cloning
Which of the following RNA polymerase catalyses the formation of transfer RNA in eukaryotes?
RNA polymerase I
RNA polymerase II
RNA polymerase I and II
RNA polymerase III
Out of 64 codons how many of them code for amino acids?
64
20
61
32
Circular DNA is found in:
Bacteria, chloroplast and mitochondria
Chloroplast and mitochondria alone
All of these
If in a DNA molecule cytosine is 18%, the percentage of adenine would be:
Isotopes used in proving semiconservative replication of DNA were:
14N 14C
14N 15N
14N 31P
14C 31P
Bacterial nucleoid has:
One single-stranded DNA
One double-stranded DNA
Two single-stranded DNA
Many double-stranded DNAs
Imagine an error occurring during DNA replication in a cell, so that where there is supposed to be a T in one of the genes there is instead a G. What effect will this probably have on the cell?
An amino acid will be missing from each of its kinds of proteins
One of its kinds of proteins might contain an incorrect amino acid
An amino acid will be missing from one of its kinds of proteins.
A sequence of pictures of polypeptide synthesis shows a ribosome holding two transfer RNAs. One tRNA has a polypeptide chain attached to it; the other tRNA has a single amino acid attached to it. What does the next picture show?
The tRNA with the amino acid leaves the ribosome
The amino acid moves over and bonds to the polypeptide chain
The tRNA with the polypeptide chain leaves the ribosome
Column-I Column-III. Genome of ϕ 174 bacteriophage A. Ribozyme, RNAaseII. Purine B. 5386 NucleotidesIII. Catalytic RNA C. Adenine and GuanineIV. Any chemical change in DNA D. MutationThe correct match is:
I - B, II - A, III - D, IV - C
I - D, II - C, III - A, IV - B
I - B, II - C, III - A, IV - D
Column-I Column-III. Operator site A. Binding site for RNA polymeraseII. Promoter site B. Binding site for repressor moleculeIII. Structural gene C. Codes for enzyme proteinIV. Regulator gene D. Code for repressor moleculesThe correct match is:
Column-I Column-III. Termination A. Aminoacyl tRNA synthetaseII. Translation B. Okazaki fragmentsIII. Transcription C. GTP dependent release factorIV. DNA replication D. RNA polymeraseThe correct match is:
I - C, II - A, III - D, IV - B
In chromosome, DNA is associated with:
A. Negatively charged proteins B. Positively charged proteins
C. Neutral proteins D. NHC protein
B, D
(2) A, B, C, D
(3) B, C, D
(4) A, B, C
Heterochromatin:
A. Is more densely packed B. Is stains dark
C. Is transcriptionally active D. Is transcriptionally inactive
A, C
A, B, C, D
B, C, D
A, B, D
In 1953, James Watson and F. Crick proposed the Double Helix model of DNA and got Nobel Prize. Their model of DNA was based on:A. X-ray diffraction of DNA produced by M. Wilkins and R. FranklinB. Griffith’s experiment.C. Hershey - Chase experimentD. Chargaff’s rule of base equivalence (A + G / T + C = 1)
In one polynucleotide chain of a DNA molecule the ratio of A + T / G + C is 0.3. What is the A + G / T + C ratio of the entire DNA molecule:
0.3
0.6
1.2
DNA polymerase:A. Is the main enzyme for RNA synthesisB. Is DNA dependent DNA polymerizing enzymeC. Is a highly efficient enzymeD. Is catalyzes a reaction with a high degree of accuracy
A, B, C
The difference(s) between mRNA and tRNA is / are that:A. mRNA has more elaborated 3-dimensional structure due to extensive base-pairing.B. tRNA has more elaborated 3-dimensional structure due to extensive pairing.C. tRNA is usually smaller than mRNA.D. mRNA bears anticodon but tRNA has codons.
B, C
In eukaryotes the gene expression is regulated at:A. Transcriptional levelB. Processing levelC. Transport of mRNA from nucleus to the cytoplasmD. Translational level
In prokaryotes, gene regulation occurs at the level of:
Transcription
Translation
Post transcription
Post translation
Characteristic(s) of most DNA is / are:A. A pairs with T by 2 hydrogen bonds.B. Antipolarity of complementary chainsC. 20Aº diameterD. 10 bps/turn
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