Genetic information in a DNA molecule is coded in the:
Sequence of nucleotides
Base pairings
Proportion of each base present
The turning pattern of the helix
In DNA replication, the Okazaki fragments on the lagging strand are joined together by:
DNA ligase
DNA polymerase
Primase
Helicase
The enzyme that catalyzes the peptide bonding in prokaryotes is located in the:
Leader region of the mRNA
Central part of tRNA
Smaller subunit of the ribosome
Larger subunit of the ribosome
In general, bacterial genes are regulated at the time of:
Transcription
Post transcription
Translation
Post translation
The insertion or deletion of a base pair into the genetic code will cause a frame shift mutation unless the number of base pairs inserted or deleted is:
One
Two
three
Ten
Consider the following statements:
I. The largest known human gene is dystrophin at 2.4 million bases
II. Repeated sequences make up very large portion of the human genome
III. There are about 2.4 million locations where single base DNA differences occur in humans
Which of the above statements are true?
I and II only
I and III only
II and III only
I, II and III
I. RNA is the genetic material of the QB bacteriophage
II. DNA chemically is less reactive and more stable than RNA
III. Viruses having RNA genome and having shorter life span mutate & evolve slowly.
I. Inheritance of a character is affected by promoter and regulatory sequences of a structural gene.II. The split-gene arrangement represents an ancient feature of the genome.
III. The process of splicing represents the dominance of RNA world.which of the above statements are true?
I. All the reference point while defining a transcription unit is made with coding strand
II. It is the presence of a promoter in a transcription unit that also defines the template and coding strands
III. Exons are said to be sequences that do not appear in mature or processed RNA
I. Deoxyribonucleoside triphosphates act as substrates as well as provide energy for polymerization reaction during DNA replication.
II. The replication of DNA is both semiconsenvative and semi- discontinuous
III. In bacterial DNA replication there are multiple ori and replication fork moves bi-directionallyWhich of the above statements are true?
Match each item in Column I with one item in Column II and chose your answer from the codes given below:
Column I
(nRNA codons)
Column II
(Amino Acid)
I. GUG
II. UGG
III. UAC
IV. GAG
1. Tryptophan
2. Valine
3. Glutamic acid
4. Tyrosine
Codes
I II III IV
1 2 3 4
2 1 4 3
2 1 3 4
1 2 4 3
If there are 999 bases in an RNA that codes for a protein with 333 amino acids and the base at position 901 is deleted such that the length of teh RNA becomes 998 bases, how many codons will be altered?
1
11
33
333
DNA fragments are
positively charged
negatively charged
neutral
either positively or negatively charged depending on their size
During DNA replication, Okazaki fragments are used to elongate
The leading strand towards replication fork
The lagging strand towards replication fork
The leading strand away from replication fork
(2) The lagging strand away from replication fork
Spliceosomes are not found in cells of
plants
fungi
animals
bacteria
The final proof for DNA as the genetic material come from the experiments of
Griffith
Hershey and chase
Avery, Macleod and McCarty
Hargobind Khorana
The association of histone H1 with a nucleosome indicates
transcription is occuring
DNA replication is occuring
the DNA is condensed into chromatin fibre
the DNA double helix is exposed
Which of the following RNAs should be most abundant in animals cell ?
rRNA
tRNA
mRNA
miRNA
Taylor conducted the experiments to prove semi-conservative mode of chromosome replication on
Vinca rosea
Vicia faba
Drosophila melanogaster
E. coli
The equivalent of a structural gene is
muton
cistron
operon
recon
How many types of nitrogenous bases are present in nucleic acid
4
3
5
6
Select the correct option
Direction of RNA synthesis
Direction of reading of the template DNA strand
(1)
5'-3'
3'-5'
(2)
(3)
(4)
Commonly used vectors for human genome sequencing are
T-DNA
BAC and YAC
Expression vectors
T/A cloning vectors
Which enzymes/s will be produced in a cell in which there is a non-sense mutation in the lac Y gene?
β-galactosidase
Lactose permease
Transacetylase
Lactose permease and transacetylase
Removal of RNA polymerase III from nucleoplasm will affect the synthesis of
hnRNA
PCR and Restriction Fragment Length Polymorphism are the methods for
study of enzymes
genetic transformation
DNA sequencing
genetic fingerprinting
Which one of the following is not a part of a transcription unit in DNA?
The inducer
A terminator
A promoter
The structural gene
If one strand of DNA has the nitrogenous base sequence as ATCTG, what would be the complementary RNA strand sequence?
TTAGU
UAGAC
AACTG
ATCGU
Removal of introns and joining of exons in a defined order during transcription is called
looping
inducing
capping
splicing
What are those structures that appear as ‘beads-on-string’ in the chromosomes when viewed under electron microscope?
Nucleotides
Nucleosomes
Base pairs
Genes
Please disable the adBlock and continue. Thank you.