In which of the following combinations, the compounds in ascending order based on their molecular weights are arranged?

  • DNA, RNA, AMP, ADP, ATP

  • DNA, RNA, ATP, ADP, AMP

  • AMP, ADP, ATP, RNA, DNA

  • AMP, ATP, ADP, DNA, RNA

If a segment of an mRNA molecule has the sequence 5’ GUACCGAUCG 3’, which of the following could have been the template DNA molecule?

  • 3’ GCUAGCCAUG 5’

  • 3’ GUACCGAUCG 5’

  • 3’ CATGGCTAGC 5’

  • 3’ CGATCGGTAC 5’

In prokaryotes, the process of replication is catalysed by the following enzymes. Identify which of the enzymes is best coordinate with the role.

 –

Joins the ends of DNA segments

 –

Synthesises DNA

 –

Erases primer and fills gaps

 –

Synthesises RNA primers

 

  • Helicase

  • DNA polymerase-I

  • DNA polymerase-II

  • Primase

hn-RNA undergoes two additional processing. Out of which, in one of them an unusual nucleotide (methyl guanosine triphosphate) is added to the 5’-end of hnRNA. This is known as

  • capping

  • tailing

  • splicing

  • termination

If there are 10,000 nitrogenous base pairs in a DNA then how many nucleotides are there

  • 500

  • 10,000

  • 20,000

  • 40,000

If there are 10,000 nitrogenous base pairs in B-DNA then its length will be

  • 340nm

  • 3400nm

  • 34000nm

  • 340000nm

Cytidine is a

  • nucleoside

  • nitrogen base

  • nucleotide

  • nucleic acid

In rRNA, thymine pairs with 

  • adenine

  • uracil

  • both 1 and 2

  • None of these

Which one of the following nucleotide sequences contains only 4 pyrimidine bases?

  • UAGCGGUAA

  • TGCCTAACG

  • GATCAATGC

  • GCUAGACAA

New strands of DNA are formed only in

  • 5’→3’ direction

  • 3’→5’ direction

  • In both directions

  • There is no specific polarity

Regulation of gene expression in eukaryotes cannot take place at

  • primary transcript level

  • splicing level

  • transport of m-RNA from nucleus to cytoplasm

  • replication level

In E.coli the conversion of lactose in galactose and glucose takes place by

  • Beta-galactokinase

  • Beta-guluctosidase

  • Beta-galactosidase

  • Beta-lactosidase

The conditions which regulate the expression of genes are

  • Environmental

  • Physiological

  • Metabolic

  • All of the above

The development and differentiation of embryo into adult organisms are result of

  • chemical regulation of expression of several sets of genes

  • Electrical and Chemical regulation of expression of several sets of genes

  • coordinated regulation of expression of several sets of genes

  • All of above

Regulation of gene expression in prokaryotes predominantly takes place at

  • transcriptional

  • translational level

  • splicing gene

  • transportation of m-RNA from cytoplasm to mesosomes

Promoter regions of lac operon can be accessed by

  • RNA polymerase

  • DNA polymerase

  • Proteins

  • All of these

The lac in lac operon refers to

  • lactose but not lactase

  • lactase but not lactose

  • lactobacillus but not lactose

  • lactose as well as laevorotatory

The i-gene in lac operon refers to

  • inducer

  • inhibitor

  • sometimes inducer sometimes inhibitor

  • neither inducer nor inhibitor

For lactose metabolism

  • all three gene products are required

  • only regulator gene products are required

  • only Beta-galactosidase are required

  • Beta-galactosidase and permease are required

In lac operon, repressor is inactivated by

  • interaction with enzyme

  • interaction with protein

  • interaction with carbohydrate

  • interaction with nucleic acid

How long the lac operon would be expressed in the presence of lactose?

  • When glucose is more than lactose concentration

  • As long as lactose is more than galactose concentration

  • As long as lactose is more than glucose concentration

  • when lactose equals glucose concentration

Lac operon is an example of

  • both positive and negative regulation

  • only negative regulation

  • only positive regulation

  • sometimes positive sometimes negative

Lac operon inhibition by repressor is an example of

  • negative regulation

  • positive regulation

  • neither positive nor negative

  • both positive and negative regulation

Regulation of lac operon can be visualised as regulation of enzyme synthesis by its

  • substrate

  • lactose

  • carbohydrates

  • All of these

Lac operon will be switched on when

  • lactose is less in the medium

  • glucose is enough in the medium

  • lactose is less than glucose

  • lactose is more than glucose

Repressor mRNA will be formed in

  • absence of inducer

  • presence of inducer

  • both 1 and 2

  • presence of lac mRNA

The order and sequence of amino acids are defined by

  • Nucleotides sequences in DNA

  • Nucleotides sequences in mRNA

  • Nucleotides sequences in template strand of DNA

  • Nucleotides sequences in non- template strand of DNA

Formation of peptide bond is

  • active process

  • passive process

  • both active and passive process

  • neither active nor passive process

Which of the following is incorrect for protein synthesis

  • Ribosomes are the cellular for protein synthesis

  • 23s rRNA act as catalyst for peptide bond formation in all organisms

  • UTR are required for efficient translation process

  • The ribosome proceeds to the elongation phase of protein synthesis

In bacteria catalytic RNA is found in

  • 60S subunit of ribosome

  • 40S subunit of ribosome

  • 30S subunit of ribosome

  • 50S subunit of ribosome

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